Results 121 to 130 of about 49,496 (211)

Addressing the Abundance Paradox Through Topology‐Guided Graph Learning for Cross‐Cohort Classification of Type 2 Diabetes

iMetaMed, EarlyView.
By shifting from highly variable taxonomic abundance to conserved ecological network topologies, our Dual‐Stream Graph Attention Network (DS‐GAT‐CP) resolves the “abundance paradox,” enabling highly accurate and cross‐regionally robust non‐invasive screening for Type 2 Diabetes. ABSTRACT Gut microbiome‐based machine learning models for Type 2 Diabetes (
Changjian Wu, Ping Wei, Xuhui Wang, Hua Hua, Junli Li   +4 more
wiley   +1 more source

Comparative Performance of the COMHON Index and the Braden Scale for Pressure Injury Risk Assessment in Critically Ill Patients: A Retrospective Observational Study Using Consecutive ICU Sampling. [PDF]

Nurs Res Pract
Serván SM, Varela SG, Torres MVC, Iglesias SH, Del Pulgar MG, Cuevas-Budhart MA, Ortega J, Renghea A, Crespo-Cañizares A.   +8 more
europepmc   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Diagnostic Accuracy of Tidal Breathing Patterns in Assessing Airflow Obstruction Compared with Spirometry. [PDF]

Int J Chron Obstruct Pulmon Dis
Dörssers BJMH, Vaes AW, Hagmeijer R, Broekhuijsen-Godding MHJM, Franssen FME, van Putten DS, Spruit MA, Simons SO.   +7 more
europepmc   +1 more source

Genetic and Clinical Characteristics of Thalassemia Trait and Construction of LASSO‐Based Model for Its Differentiating From Iron Deficiency Anemia in Northern China

Journal of Clinical Laboratory Analysis, EarlyView.
This study revealed a β‐thalassemia‐trait‐dominated genetic spectrum in Northern‐Chinese patients with microcytic hypochromic anemia, with _αSEA/αα, HBB:c.316_197C>T and HBB:c.124_127delTTCT being the most prevalent α‐ and β‐globin genotypes. Using LASSO regression, we constructed a nomogram based on four routine complete‐blood‐count parameters (RBC ...
Wen‐jie Yu, Feng‐qi Zhang, Jia‐feng Niu, Rui Ma, Yin‐ting Ma, Guang‐ping Li, Yan Long   +6 more
wiley   +1 more source

Validating an early pregnancy HbA1c as the screening test for gestational diabetes mellitus: findings from PRISMA Pakistan cohort. [PDF]

BMJ Open
Naz S, Yazdani NS, Hoodbhoy Z, Ghebremihael-Weldeselassie Y, Mazhar A, Hotwani A, Jehan F, Nisar MI, Iqbal R.   +8 more
europepmc   +1 more source

From Single‐Antigen Beads to the Physical Crossmatch: A Class‐Specific MFI Framework for Virtual Crossmatching in Kidney Transplantation

Journal of Clinical Laboratory Analysis, EarlyView.
Single‐antigen bead (SAB) assays, flow cytometric (FCXM), and complement‐dependent cytotoxicity (CDC) crossmatches form an ordered continuum of analytic sensitivity accompanied by rising donor‐specific antibody (DSA) strength. To predict B‐cell crossmatch positivity, this study provides both a single overall maximum MFI threshold and a jointly ...
Nuchjarnun Choktaweesak, Supasiri Ounjai, Patcharipa Chanaturakarnnon, Nattiya Hirankarn, Suwasin Udomkarnjananun   +4 more
wiley   +1 more source

First‐Trimester Crown‐Rump Length and Large for Gestational Age Newborns: What Correlation?

Journal of Clinical Ultrasound, EarlyView.
Our research found for the first time that uneventful pregnancies with LGA neonates are characterized by larger than expected CRL at the first trimester. CRL is one of the new markers that can be used to early identify fetuses at risk of increased fetal growth.
Marika Ylenia Rovetto, Laura Sarno, Giuseppe Gabriele Iorio, Giuliana Orlandi, Caterina Fulgione, Mariarosaria Motta, Anna Luna Tramontano, Giuseppe Rizzo, Ilenia Mappa, Maurizio Guida, Giuseppe Maria Maruotti   +10 more
wiley   +1 more source

Normative scores and clinical cut‐offs of the Cyclothymic–Hypersensitive Temperament Questionnaire in adolescence

JCPP Advances, EarlyView.
Abstract Background The Cyclothymic–Hypersensitive Temperament (CHT) is a multidimensional, transdiagnostic affective disposition characterized by mood instability, interpersonal sensitivity, heightened emotional reactivity and impulsive behaviors. The CHT Questionnaire (CHTQ) currently lacks of normative references and empirically derived thresholds ...
Anna Pezzella, Vincenzo Paolo Senese, Gabriele Masi, Annarita Milone, Giulia Mutti, Pietro Buono, Gianluca Sesso, Carmela Bravaccio, Raffaella Iuliano, Gennaro Catone, Simone Pisano   +10 more
wiley   +1 more source

Predictive Value of Perioperative Systemic Inflammation Response Index Dynamics for Postoperative Pulmonary Infection Following Esophagectomy: A Multicenter Retrospective Cohort Study. [PDF]

J Inflamm Res
Wang C, Zhang L, Zhang C, Li G, Zhou R.
europepmc   +1 more source