Results 81 to 90 of about 49,496 (211)

Autoantibodies to Joint‐Related Peptides Are Associated With Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

Arthritis &Rheumatology, EarlyView.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA) and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serologic markers. Methods We analyzed serum and plasma from three cohorts: presymptomatic individuals who later developed RA ...
Outi Sareila, Linda Johansson, Anders Lundquist, Monica Leu Agelii, Lei Cheng, Yibo He, Erik Lönnblom, Maria Andersson, Jan Kihlberg, Anders Esberg, Inger Gjertsson, Rikard Holmdahl, Solbritt Rantapää‐Dahlqvist   +12 more
wiley   +1 more source

Differentiation and Pathologic Significance of Tissue‐Resident Memory‐Like CD8+ T Cells in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Tissue‐resident memory T (TRM) cells have been implicated in organ‐specific immune pathology; however, the pathologic relevance of TRM‐like CD8+ T cells in systemic lupus erythematosus (SLE) remains unclear. We investigated their differentiation mechanisms and pathologic significance in SLE, including associations with disease activity and ...
Yuya Fujita, Kaoru Yamagata, Satoshi Kubo, Ippei Miyagawa, Koshiro Sonomoto, Yurie Satoh‐Kanda, Masanobu Ueno, Shumpei Kosaka, Aya Nawata, Yoshiya Tanaka, Shingo Nakayamada   +10 more
wiley   +1 more source

Intravascular Lithotripsy in Left Main Stem Percutaneous Coronary Intervention

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background IVL is increasingly used for coronary calcium modification; however, prospective data for its use in LMS lesions are lacking. Aims To evaluate the feasibility, safety, and mechanical efficacy of intravascular lithotripsy (IVL) for calcium modification in calcified distal left main stem (LMS) percutaneous coronary intervention ...
Claudia S Cosgrove, Retesh Bajaj, Ganeev Malhotra, Francis R Joshi, Akiko Maehara, Andrew McNeice, Margaret McEntegart, Gao Ong, Novalia Sidik, Julian W Strange, Simon Walsh, Ian Webb, Simon Wilson, Jiawei Wu, James C Spratt   +14 more
wiley   +1 more source

Diagnostic Agreement and Threshold Correspondence Between Resting Full‐Cycle Ratio and Nicorandil‐Based Fractional Flow Reserve in Intermediate Coronary Stenosis: A Prospective Single‐Center Registry

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background RFR has shown good aggregate agreement with FFR, including in prior Asian cohorts using intracoronary nicorandil. Where RFR‐FFR disagreement is concentrated relative to the FFR 0.80 decision boundary, and how the two binary thresholds correspond, remain incompletely characterized. Methods In a prospective single‐center registry, 300
Yonghoon Shin, Onyou Kim, Gi Won Yu, Yun Won Lee, Jung‐Joon Cha, Hyung Joon Joo, Jae Hyoung Park, Soon Jun Hong, Cheol Woong Yu   +8 more
wiley   +1 more source

Application of Four Frailty Assessment Tools in Elderly Patients With Coronary Heart Disease PCI and Its Relationship With Quality of Life

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Frailty is highly prevalent among elderly patients with coronary heart disease (CHD) undergoing percutaneous coronary intervention (PCI) and is associated with adverse clinical outcomes and impaired health‐related quality of life.
Meixun Huang, Chunyan Zhao, Tingting Xu, Lang Liu, Yating Wu, Xiaohuan Qin   +5 more
wiley   +1 more source

Utilizing innovative two curves in nomogram

Frontiers in Medicine
ObjectiveNomograms are valuable tools in clinical research for predicting patient outcomes. Understanding threshold values within these models is crucial for assessing the model’s effectiveness and practical application in clinical environments.MethodsWe
Tianhan Zhou, Zhongkai Ni, Hao Fan, Hai Huang, Haimin Jin   +4 more
doaj   +1 more source

Long‐Term Prognostic Value of Angiography‐Derived Quantitative Flow Ratio and Radial Wall Strain in Untreated Intermediate Coronary Stenoses: A Retrospective Cohort Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Quantitative flow ratio (QFR) measures angiography‐derived coronary physiology, whereas radial wall strain (RWS) characterizes cyclic lumen deformation. We investigated their complementary long‐term prognostic information in untreated intermediate coronary stenoses and assessed the internal validity of their combined prediction ...
Yixing Chen, Yanqing Wu, Daqiu Chen, Feng Wu, Xianhua Ye, Tao Ye, Qixiang Song, Shumin Fan, Shunxiang Luo, Shanghua Xu   +9 more
wiley   +1 more source

Artificial intelligence‐based screening of paroxysmal nocturnal hemoglobinuria clones: Development and comparative evaluation of machine learning models

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract The diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) relies on detecting cells deficient in GPI‐anchored proteins and is currently based on manual, time‐consuming interpretation requiring specialized expertise. This study aimed to develop machine learning models to identify PNH clones in granulocytes and monocytes using flow cytometry ...
Felipe Magalhães Furtado, Fernanda de Oliveira Resende, Camila Santos Nobre, Alan Carvalho Dias, André Luiz Pinto, Adamara Felício   +5 more
wiley   +1 more source

Psychometric Evaluation of the Eating Disorder‐15 (ED‐15): Factor Structure, Measurement Invariance, and Eating Disorder Caseness in Treatment Seekers

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study examines the factor structure, measurement invariance, and discriminative ability of the Eating Disorder‐15 (ED‐15) questionnaire in a large transdiagnostic clinical population of treatment‐seeking adults. Method The sample consisted of 2015 participants aged 17–79 (Mage = 30.73 years; 77.0% women; 71.1% in Australia ...
Jamie‐Lee Pennesi, Laura Edney, Yuan Zhou, David L. Hegarty, Benjamin Buchanan, Tracey D. Wade   +5 more
wiley   +1 more source

Machine learning‐based prediction of elevated N terminal pro brain natriuretic peptide among US general population

ESC Heart Failure, Volume 12, Issue 2, Page 859-868, April 2025.
Abstract Aims Natriuretic peptide‐based pre‐heart failure screening has been proposed in recent guidelines. However, an effective strategy to identify screening targets from the general population, more than half of which are at risk for heart failure or pre‐heart failure, has not been well established.
Yuichiro Mori, Shingo Fukuma, Kyohei Yamaji, Atsushi Mizuno, Naoki Kondo, Kosuke Inoue   +5 more
wiley   +1 more source