Results 61 to 70 of about 1,316,712 (317)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Building RECOVERY: development of the registry of eating disorders and their co-morbidities OVER time in youth

Journal of Eating Disorders
Background Eating disorder (ED) research is limited by the lack of longitudinal cohort studies, particularly those in adolescents, and the lack of inclusion of multiple perspectives and diagnoses.
Tracy K. Richmond, Emily Farbman Kadish, Monique Santoso, Carly E. Milliren, Meredith Kells, Genevieve Alice Woolverton, Elizabeth R. Woods, Sara F. Forman   +7 more
doaj   +1 more source

Feasibility and acceptability of multidisciplinary team training in health coaching: Case study in adolescent rheumatology

Future Healthcare Journal
The central importance of the biopsychosocial model of chronic disease is increasingly recognised in the management of long-term conditions (LTC), which are often associated with chronic pain, fatigue and disability.
Aicha Bouraoui, Penny Newman, Corinne Fisher, Aisha Shah, Rhea Burman, Sophia Mavrommatis, Debajit Sen   +6 more
doaj   +1 more source

Endoscopic Repair of the Proximal Hamstring

Video Journal of Sports Medicine, 2021
Background: Proximal hamstring injuries are increasingly common. While open repair with suture anchors placed in the ischial tuberosity has long been the gold standard technique for surgical management, endoscopic techniques can allow for smaller ...
Steven F. DeFroda MD, MEng, Benjamin S. Kester MD, Alexander C. Newhouse BS, Daniel M. Wichman BS, Sunikom Suppaiksorn MD, Shane J. Nho MD, MS   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Transition into adult healthcare services in Scotland –findings from a study concerning service users at the Scottish Spina Bifida Association [PDF]

, 2014
Background and Aims Literature on interventions that enable young people with Spina Bifida and/or Hydrocephalus to have smooth transition, into adult healthcare services, stress the need for the process to start early and to include all family members ...
Wynd , Andrew H D, Carachi, Robert, Levy, Sharon; id_orcid, Levy, Sharon, ,   +4 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Sexual Dysfunction Among Adolescent and Young Adult Men Diagnosed with Cancer

, 2022
Purpose: Adolescent and young adult (AYA) cancer patients frequently demonstrate sexual dysfunction; however, there is a lack of data quantifying the severity and frequency.Methods: Males aged 18-39 years, diagnosed with cancer of any kind and who were ...
Dubin, Justin Michael, Monga, Varun, Rainer, Quinn Carroll, Shoag, Jamie, Rodriguez, Alejandro Aaron, Ramasamy, Ranjith, Alperstein, Warren, Balaji, Navin Chakravarthy, Greer, Aubrey, Kava, Bruce Richard, Nackeeran, Sirpi, Pearlman, Amy Marcia, Terry, William, Troesch, Victoria, Paz, Lisa, Clifford, Lindsey, Patel, Premal   +16 more
core   +1 more source

Growing up in a larger body: youth- and parent-reported triggers for illness and barriers to recovery from anorexia nervosa

Journal of Eating Disorders
Background A significant portion of youth with anorexia nervosa (AN) or atypical anorexia nervosa (AAN) have history of ‘overweight/obesity’ (i.e., body mass index ≥ 85th percentile for age-and-sex) prior to the onset of the eating disorder (ED ...
Grace B. Jhe, Michelle Recto, Julia A. Vitagliano, Kelsey L. Rose, Tracy Richmond, Melissa Freizinger, Jessica Lin   +6 more
doaj   +1 more source