Results 81 to 90 of about 9,259,824 (359)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The dimensions of successful young adult development: A conceptual and measurement framework
In this article, we draw on the theoretical and empirical literature to name what appear to be core dimensions of successful young adult development.
P. Scales +5 more
semanticscholar +1 more source
Children’s and young adult literature collections have an important place in an academic library. Most often, these collections go unnoticed by many in academia, who may regard children’s literature as irrelevant to the mission of the academic library ...
Atkinson, Melissa
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Antiracist Curriculum Implementation for Pediatric Residents
Objectives Racism has been recognized as a public health crisis, with calls for greater focus on antiracism in medical training. We sought to evaluate a longitudinal antiracist curriculum among pediatric residents.
Nicholas Szoko +4 more
doaj +1 more source
Quality of life in adolescent and young adult cancer patients: a systematic review of the literature
Introduction Adolescent and young adult (AYA) cancer survivors experience many unique challenges and quality of life (QoL) effects that persist beyond cancer diagnosis and treatment.
G. Quinn +4 more
semanticscholar +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Background A significant portion of youth with anorexia nervosa (AN) or atypical anorexia nervosa (AAN) have history of ‘overweight/obesity’ (i.e., body mass index ≥ 85th percentile for age-and-sex) prior to the onset of the eating disorder (ED ...
Grace B. Jhe +6 more
doaj +1 more source
Osteoid osteomas are benign bone lesions that commonly occur in the lower extremities and spine, with the radiographic evidence of a central nidus surrounded by circumferential reactive bone.
Alexander C. Newhouse, B.S. +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

