Results 11 to 20 of about 934,635 (312)

Cardiologic Long-Term Follow-Up of Patients Treated With Chest Radiotherapy: When and How?

Frontiers in Cardiovascular Medicine, 2021
Introduction: Radiotherapy may cause valvular (VHD), pericardial, coronary artery disease (CAD), left ventricular dysfunction (LVD), arrhythmias. The risk of radiation induced heart disease (RIHD) increases over time.
Chiara Lestuzzi, Maurizio Mascarin, Elisa Coassin, Maria Laura Canale, Fabio Turazza   +4 more
doaj   +1 more source

Medical trauma in young adults with inflammatory bowel disease: The role of trauma-informed care

Health Care Transitions
Medical trauma is a profound concern for those with chronic conditions like inflammatory bowel disease (IBD), especially young adults. This trauma, arising from both the disease itself and necessary medical interventions, manifests as an accumulation of ...
Amy K. Bugwadia, Sydney Reed, Mara Shapiro, Sneha Dave, Nikhil Jayswal, David Kohler, Laurie Keefer   +6 more
doaj   +1 more source

Social Care and Young Adults with Neuromuscular Conditions Diagnosed in Childhood: A Co-Produced Scoping Review

Journal of Long-Term Care
Context: The social care needs of young adults with neuromuscular conditions (NMCs) are poorly evidenced. To address the paucity in research, it is first necessary to consolidate current understanding of social care and its presence/absence in the lives
George Peat, Suzanne Glover, Caterina Radu, Steven Jones, Grace Binney, James Parkin, Kirsty Liddiard, Lorna Katherine Fraser, David Abbott   +8 more
doaj   +1 more source

KIF5A and ALS2 Variants in a Family With Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis

Frontiers in Neurology, 2018
This paper describes the clinical evolution and the novel genetic findings in a KIF5A mutated family previously reported as affected by spastic paraparesis only.
Marta Simone, Antonio Trabacca, Elena Panzeri, Luciana Losito, Andrea Citterio, Maria Teresa Bassi   +5 more
doaj   +1 more source

Immune and metabolic markers for identifying and investigating severe Coronavirus disease and Sepsis in children and young people (pSeP/COVID ChYP study): protocol for a prospective cohort study

BMJ Open, 2023
Introduction Early recognition and appropriate management of paediatric sepsis are known to improve outcomes. A previous system’s biology investigation of the systemic immune response in neonates to sepsis identified immune and metabolic markers that ...
Richard Skone, Daniel White, Bethan Phillips, Jennifer Evans, Robert Andrews, Benjamin Saunders, Kerry Hood, Mallinath Chakraborty, Sarah Edkins, Barbara Paquete, Sian Foulkes, Anna Barrow, Siske Struik, Valerie O'Donnell, Sara Ali, Patrícia R S Rodrigues, Angela Strang, Summia Zaher, Simran Sharma, Luke C Davies, Linda Moet, James E McLaren, Gareth L Watson, Peter Ghazal, Edward Parkinson, Sivakumar Oruganti, William John Watkins, Selyf Shapey, Rim al Samsam, Malcolm Gajraj, Michelle Jardine, Jong Eun Song, Lloyd Abood, Sarah Joanne Kotecha, Awen Evans, Iona Buchanan, Susan Bowes, Begum Ali, Maya Gore, Rhian Thomas-Turner, Federico Liberatore, Thomas Woolley   +41 more
doaj   +1 more source

Stroke in Young Adults

Journal of Clinical Medicine, 2023
Stroke in young adults is associated with significant morbidity, and its prevalence is rising in the United States. This is partly attributed to a rise in the prevalence of traditional risk factors including hypertension, hypercholesterolemia, obesity, diabetes mellitus, smoking and heart disease.
Syed Bukhari, Shadi Yaghi, Zubair Bashir
openaire   +2 more sources

Necroptotic and Apoptotic Pathways in Sepsis: A Comparative Analysis of Pediatric and Adult ICU Patients

Biomedicines
Background: Necroptosis, a regulated form of inflammatory cell death, is increasingly recognized as a key driver of sepsis and critical illness. The balance between necroptosis and apoptosis may influence immune responses and outcomes in ICU patients ...
George Briassoulis, Konstantina Tzermia, Kalliopi Bastaki, Marianna Miliaraki, Panagiotis Briassoulis, Athina Damianaki, Eumorfia Kondili, Stavroula Ilia   +7 more
doaj   +1 more source

Study protocol of Diabetes LEAP: a longitudinal study examining emotional problems in adolescents with type 1 diabetes and their parents/caregivers

BMC Pediatrics, 2019
Background Type 1 diabetes (T1D) is a chronic metabolic condition requiring intensive daily self-care to avoid both high and low blood glucose levels.
Giesje Nefs, Linh Nguyen, Per Winterdijk, Esther Hartman, Theo Sas, Roos Nuboer, Ineke De Kruijff, Willie Bakker-van Waarde, Henk-Jan Aanstoot, Frans Pouwer   +9 more
doaj   +1 more source

Fluid Creep as an Independent Predictor of Fluid Overload and Mortality in Critically Ill Patients: A Cohort Study

Life
Background: Fluid overload (FO) is a frequent ICU complication and an important predictor of adverse outcomes. While classically attributed to resuscitative fluids, recent data emphasize the contribution of non-therapeutic “fluid creep” from medication ...
George Briassoulis, Theodora Antonopoulou, Joanna Velegraki, Stavroula Ilia, Eumorfia Kondili   +4 more
doaj   +1 more source

Sequential genomic analysis using a multisample/multiplatform approach to better define rhabdomyosarcoma progression and relapse

npj Precision Oncology, 2023
The genomic spectrum of rhabdomyosarcoma (RMS) progression from primary to relapse is not fully understood. In this pilot study, we explore the sensitivity of various targeted and whole-genome NGS platforms in order to assess the best genomic approach of
Henry de Traux de Wardin, Josephine K. Dermawan, Marie-Sophie Merlin, Leonard H. Wexler, Daniel Orbach, Fabio Vanoli, Gudrun Schleiermacher, Birgit Geoerger, Stelly Ballet, Delphine Guillemot, Eléonore Frouin, Stacy Cyrille, Olivier Delattre, Gaelle Pierron, Cristina R. Antonescu   +14 more
doaj   +1 more source