Results 131 to 140 of about 1,765,915 (266)

Experimental Exposure to Noise Affects Hunting Behavior Already From a Young Age in a Nocturnal Acoustic Predator. [PDF]

Ecol Evol
Orlando G, Passarotto A, Morosinotto C, Dominoni DM, Karell P.   +4 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Educational and occupational outcomes during early adulthood following surgically verified endometriosis at a young age-A register-based study. [PDF]

Acta Obstet Gynecol Scand
Rasp E, Saavalainen L, Rönö K, Gissler M, Härkki P, But A, Heikinheimo O.   +6 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Long-Term Outcome After Mustard Repair at Young Age: Longitudinal Follow-Up Into the Fifth Decade After Surgery. [PDF]

JACC Adv
Ünlütürk S, Kauling RM, Cuypers JAAE, van den Bosch AE, Hirsch A, Driessen MMP, Pelosi C, Bowen DJ, Bogers AJJC, Helbing WA, Kardys I, Roos-Hesselink JW.   +11 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Distinct clinicopathological features and treatment differences in breast cancer patients of young age. [PDF]

Sci Rep
Humlevik ROC, Svanøe AA, Aas T, Heie A, Sæle AKM, Akslen LA, Wik E, Hoivik EA.   +7 more
europepmc   +1 more source

Presynaptic Dopaminergic Dysfunction Was Overestimated in Huntington's Disease Presenting as Young Age-Onset Parkinsonism. [PDF]

J Mov Disord, 2022
Kim T, Choi BJ, Lyoo CH.
europepmc   +1 more source

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

Letter to the editor on "Male preference for TERT alterations and HBV integration in young-age HBV-related HCC: implications for sex disparity". [PDF]

Clin Mol Hepatol
Mai Q, Zheng J, Tang M, Liu Y.
europepmc   +1 more source