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Age & Opportunity annual report 2011
Strategic report for Age & Oppertunity ...
Age & Opportunity
core
Background and Study Aim. Physical abilities and fundamental skills are essential characteristics of football players requiring in-depth analysis, but the results of previous short-term investigations lack a comprehensive overview.
Sulistiyono Sulistiyono +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Manifestation of Life Meaning Crisis at Youth
Background. In the context of the value pluralism in modern society, the importance of the ability to determine one's own value-semantic orientations, to make an independent choice between various sources of meaning and build one's life project on their ...
Irina A. Skirtach, Veronika A. Pakhomova
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A clinical case of acute polyneuropathy, with the onset of bilateral facial nerve palsy in an early childhood [PDF]
BACKGROUND: The differential diagnosis of peripheral nervous system damage depends on a thorough collection of history, comprehensive assessment of clinical manifestations, and dynamic examination of the patient. This article describes a clinical case of
Elena Yu. Skripchenko +12 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Disabled or Young? Relative Age and Special Education Diagnoses in Schools [PDF]
This study extends recent findings of a relationship between the relative age of students among their peers and their probability of disability classification. Using three nationally representative surveys spanning 1988-2004 and grades K-10, we find that
Lipscomb, Stephen, Dhuey, Elizabeth
core
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source

