Results 71 to 80 of about 9,396,887 (265)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Kilkenny: age friendly county strategy [PDF]
, 2010 This document outlines a new and ambitious plan to improve the lives and well being of all older adults in Kilkenny. The strategy has been developed as a result of detailed consultation with the older people of Kilkenny, the agencies and service ...
Kilkenny Age Friendly County Alliance
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Children and Young People’s Participation in Scotland: Frameworks, standards and principles for practice (Summary Report) [PDF]
, 2012 A report by Dr Greg Mannion. Providing greater support for children and young people's participation in Scotland is seen by Scotland’s Commissioner for Children and Young People as a way of addressing children’s rights, improving practice ...
Mannion, Greg
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Growth and nutrition: Preliminary findings from the 2016 Young Lives survey (round 5): United Andhra Pradesh [PDF]
, 2017 This fact sheet presents findings from the fifth round of the Young Lives survey of children in United Andhra Pradesh in 2016. Young Lives has followed two cohorts of children since 2002.
Young Lives, Young, Young Lives,
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Driving into the sunset: Supporting cognitive functioning in older drivers [PDF]
, 2011 Copyright @ 2011 Mark S. Young and David Bunce - This article has been made available through the Brunel Open Access Publishing Fund.The rise in the aging driver population presents society with a significant challenge-how to maintain safety and mobility
Mark S. Young +5 more
core +1 more source
Acute coronary syndrome in young patients: clinical features and risk factors
Кардиоваскулярная терапия и профилактика, 2018 Aim. To study the clinical features and risk factors (RF) associated with the development of acute coronary syndrome (ACS) in young patients.Material and methods. The study included 474 patients with ACS.
I. V. Ponomarenko +2 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source