Results 141 to 150 of about 1,114,646 (307)

Youth workers and stress

, 2008
Much has been written about the theory and practice of youth work, and there has been a particular focus on the youth worker/young person interaction.
Bowie, Vaughan
core  

Targeted Degradation of STING by a Neutrophil Membrane‐Coated Nanoplatform Suppresses Microglial Pyroptosis After Subarachnoid Hemorrhage

Advanced Science, EarlyView.
MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang, Kaikun Yuan, Haoyu Zou, Hanfeng Qin, Jiale Liu, Jianda Sun, Feifan Zhang, Yuankui Wang, Tong Wang, Jiaxing Dai, Chunxu Li, Yichi Chen, Yingfeng Tu, Huaizhang Shi   +13 more
wiley   +1 more source

Family background and peer victimization are associated with generalized trust from adolescence to adulthood

Communications Psychology
Trust in others plays an important role in psychological development. However, longitudinal and developmentally informed research on trust remains limited and fragmented across disciplines.
David Bürgin, Laura Bechtiger, Clarissa Janousch, Annekatrin Steinhoff, Maria Picazo Mora, Denis Ribeaud, Manuel Eisner, Lilly Shanahan   +7 more
doaj   +1 more source

Socioeconomic Status and Youth Aggression in Australia

, 2002
It is perhaps surprising, given the widespread concern about youth violence, that there has been little or no research into the effect of socioeconomic status on youth aggression.
Demosthenous, Catherine, Demosthenous, Hellene, Bouhours, Thierry   +2 more
core  

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

Theory of Change Co-Created by Young People: Youth-led input to Oxfam's Youth Participation and Leadership Meta Theory of Change

, 2019
Oxfam's Youth Participation and Leadership Meta Theory of Change bring together the views and expertise of youth activists from 16 countries, Oxfam programming, advocacy and campaigns staff, and theory of change experts.
Oxfam Youth as Active Citizens Community of Practice
core   +1 more source

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

The National Youth Work Curriculum: A process-based curriculum?

, 2020
In this article, Jon Ord explores different theories and forms of curricula and uses these to analyse and critique the new National Curriculum for Youth Work that has just been published by England's National Youth Agency (NYA).
Ord, Jon
core  

ABCABC Stacking‐Enabled Non‐Centrosymmetry 3R‐ZnIn2S4 Nanosheets for Piezocatalytic Uranium Extraction

Advanced Science, EarlyView.
The ABCABC stacking sequence in 2D ZnIn2S4 nanosheets creates intrinsic non‐centrosymmetry, enabling robust piezocatalysis under weak mechanical agitation. The nanosheets achieve a H2O2 yield of 276.7 µmol g−1 h−1 and uranium extraction capacity of 763.2 mg g−1 via a dual mechanism of direct piezoreduction and in situ H2O2 complexation.
Song Li, Huaijuan Zhou, Yingting Yang, Yanhong Lv, Zdeněk Sofer, Jianyun Zheng, Jinhua Li   +6 more
wiley   +1 more source

Kirigami‐Cut Pattern Designs for the Enhancement of Sensing Performance Induced by Programmable Out‐of‐Plane Deformation

Advanced Science, EarlyView.
Different kirigami patterns are proposed and the parameters are optimized by comparing the out‐of‐plane deformation behavior. Then, the proposed patterns are fabricated on PVDF film using laser technology. The deformed kirigami‐cut PVDF is embedded into PDMS to construct pressure senor.
Xiaodong Huang, Yuhao Wu, Shan Lu, Liguo Qin, Xin Ge, Guangneng Dong, Qiao Hu   +6 more
wiley   +1 more source