Results 131 to 140 of about 123,043 (297)

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

open access: yesAdvanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu   +10 more
wiley   +1 more source

Escolarização de jovens e adultos

open access: yesRevista Brasileira de Educação, 2000
The article covers the systematic and organized processes of general education offered to youth and adults, carried out in Brazil, in the light of public policies.
Sérgio Haddad, Maria Clara Di Pierro
doaj  

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

open access: yesAdvanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang   +8 more
wiley   +1 more source

Statistical Literacy: Developing A Youth And Adult Education Statistical Project

open access: yes, 2015
This article focuses on the notion of literacy - general and statistical - in the analysis of data from a fieldwork research project carried out as part of a master's degree that investigated the teaching and learning of statistics in adult education ...
de Carvalho D.L., Conti K.C.
core  

Advancing Equity in Education: Progress Towards Inclusive and Equal Access for the Vulnerable in South Africa

open access: yesEducation Sciences
This study evaluates South Africa’s progress toward achieving SDG 4.5 by examining disparities in educational access and outcomes for vulnerable groups, including girls, children with disabilities, rural populations, and low-income households.
Abieyuwa Ohonba
doaj   +1 more source

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu   +4 more
wiley   +1 more source

Reflections on the development of a proposal for STS teaching developed in the context of youth and adult education

open access: yesInvestigações em Ensino de Ciências, 2016
The paper presents reflections on the joint STS triad based on data collected in intervention research carried out in a high school class of Youth and Adult Education. The subjects were students, the teacher of the class and the teacher-researcher.
Maria de Lourdes Oliveira Porto   +1 more
doaj  

What is Quality in Youth and Adult Education?

open access: yes, 2014
This paper reports a case study focused on teaching quality as observed at a Centerfor Supplemental Education (CES), an educational institution located in thecity of Rio de Janeiro, Brazil. The investigation attempted to identify theconcept of quality in education today, the polysemy of meanings coveredby the term, the various approaches reported in ...
openaire   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

open access: yesAdvanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng   +8 more
wiley   +1 more source

Alternatives to secure youth detention in Tasmania [PDF]

open access: yes, 2013
The Alternatives to Secure Youth Detention in Tasmania Inquiry originated from a request by the Minister for Children to the Commissioner for Children for advice in relation to the role of secure detention within Tasmania’s youth justice system.
Elizabeth Daly
core  

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