Results 51 to 60 of about 121,098 (314)

Identification and risk assessment of the investment project of opening a sports club

open access: yesУченые записки Российской академии предпринимательства, 2021
The article substantiates the importance and significance of aspects related to the identification andassessment of risksofan investment project. In the article, the author considers the identification and risk assessment of the investment project of ...
I. Yu. Kuzovleva
doaj  

Editorial: Digital Child- and Adulthood—Risks, Opportunities, and Challenges

open access: yesMedia and Communication, 2022
This thematic issue discusses risks, opportunities, and challenges of digital child- and adulthood based on different theoretical and methodological perspectives.
Claudia Riesmeyer   +2 more
doaj   +1 more source

Mining mobile youth cultures [PDF]

open access: yes2014 IEEE International Conference on Big Data (Big Data), 2014
In this short paper we discuss our work on co-research devices with a young coder community, which help investigate big social data collected by mobile phones. The development was accompanied by focus groups and interviews on privacy attitudes and aims to explore how youth cultures are tracked in mobile phone data.
Tobias Blanke   +3 more
openaire   +2 more sources

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

open access: yesAdvanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen   +19 more
wiley   +1 more source

Complex connections : meaningful youth participation for mental health promotion [PDF]

open access: yes, 2012
This paper explores the role of youth participation for the promotion of mental health and wellbeing, considering the benefits and challenges of participation for young people, services and organisational culture.
Blanchard, Michelle   +5 more
core  

The use of synchronized swimming exercises in the process of students physical education

open access: yesBIO Web of Conferences, 2020
The article presents an analysis of the motives, needs, interests, beliefs and students valuable orientations to the physical culture and sport. The study showed that it is necessary to modernize the process of physical education and improve some ...
Raspopova Evgeniya   +2 more
doaj   +1 more source

A review of the research in teaching and learning the negative numbers: an “action research” concerning the application of the geometrical model of the number line

open access: yesDidattica della Matematica, 2022
The notion of negative numbers is one of the most fundamental in mathematics. For many years, they have caused confusion and they have been an object of controversy among great researchers, until the development of symbolic algebra led to their ...
Athanasios Gagatsis, Maria Alexandrou
doaj   +1 more source

A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis

open access: yesAdvanced Science, EarlyView.
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang   +7 more
wiley   +1 more source

Philosophy Underlying the Proposal To Computerise the Barbadian Public School System [PDF]

open access: yes, 1996
This document articulates the philosophy underlying the decision by Barbados’ Ministry of Education, Youth Affairs and Culture to computerize the nation’s public schools.
Barbados, Ministry of Education, Youth Affairs and Culture
core  

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

open access: yesAdvanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu   +10 more
wiley   +1 more source

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