A Genetically Encoded Biosensor for Characterizing Transport and Metabolism of Glutarate
Here, a genetically encoded glutarate biosensor, Glusor, is developed based on transcriptional regulator CsiR. Glusor can quantify glutarate concentrations with good accuracy and precision. Then, the role of KgtP and YnfM are identified and characterized by using Glusor. Glusor also allows glutarate spatiotemporal resolution in live cells, facilitating
Kaiyu Gao+12 more
wiley +1 more source
School Suspension as a Predictor of Young Adult Homelessness: The International Youth Development Study. [PDF]
Heerde JA+6 more
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A Literature Review on the Role of Hope in Promoting Positive Youth Development across Non-WEIRD Contexts. [PDF]
Bowers RM, Bowers EP.
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This article examines the central role of RIPK1 in the pathogenesis of sepsis‐induced lung injury. It elucidates how RIPK1 initiates an inflammatory cascade by activating JAK1‐STAT3 signaling, leading to CXCL1‐mediated neutrophil infiltration. Importantly, it demonstrates that pharmacological inhibition of RIPK1 effectively attenuates inflammation and ...
Hao Sun+15 more
wiley +1 more source
Subjective Outcome Evaluation of a Positive Youth Development Program in Mainland China: Evidence in the Post-Pandemic Era. [PDF]
Shek DTL, Tang YT, Zhu X, Gong Z.
europepmc +1 more source
This work introduces Bi2Te3, a novel topological quantum insulator, as an advanced anode for aqueous aluminum‐ion batteries (AAIBs). The study highlights the pivotal role of hydronium ions, generated through the hydrolysis of hydrated aluminum ions, in the charge storage process.
Puja De+3 more
wiley +1 more source
Explainable machine learning prediction of internet addiction among Chinese primary and middle school children and adolescents: a longitudinal study based on positive youth development data (2019-2022). [PDF]
Liu J+10 more
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Cyberbullying and internet gaming disorder in Chinese youth: The role of positive youth development attributes. [PDF]
Xiang GX+6 more
europepmc +1 more source
This study systematically explores the action mechanism of Pon3 and its regulatory targets in spinal cord injury (SCI). It demonstrates that Dnmt1 regulates Pon3 expression by modulating methylation levels, thereby inhibiting S1PR1‐mediated pyroptosis and improving SCI prognosis.
Birong Peng+8 more
wiley +1 more source