Results 31 to 40 of about 1,801,862 (314)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Evolving brain function and connectivity patterns during mentalizing in children and adults

Communications Biology
Mentalizing, the ability to infer others’ thoughts and intentions, relies on a network of brain regions whose functional connectivity changes across development.
Réka Borbás, Plamina Dimanova, Dennis Saikkonen, Elena Federici, Sofia Scatolin, Nora M. Raschle   +5 more
doaj   +1 more source

Rural-origin health professional students’ perceptions of a support programme offered by Umthombo Youth Development Foundation

African Journal of Primary Health Care & Family Medicine, 2017
Background: Staffing of rural healthcare facilities is a challenge, with literature supporting the selection and training of rural-origin students. The Umthombo Youth Development Foundation (UYDF) scholarship scheme supports rural students to train as ...
Dumisani M. Gumede, Andrew J. Ross, Laura M. Campbell, Richard G. MacGregor   +3 more
doaj   +1 more source

The Struggle Report: Findings and Recommendations by NYC Youth for New York Job Development Programs [PDF]

, 2013
To better understand the challenges and opportunities all youth face in finding employment, FUREEous Youth and the Community Development Project (CDP) at the Urban Justice Center developed a participatory action research project.

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Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Attitudes Toward COVID-19 Vaccination Among Young Adults in Zurich, Switzerland, September 2020

International Journal of Public Health, 2021
Objectives: Young adults are essential to the effective mitigation of the novel coronavirus (SARS-CoV-2/COVID-19) given their tendency toward greater frequency of social interactions. Little is known about vaccine willingness during pandemics in European
Cesar Leos-Toro, Denis Ribeaud, Laura Bechtiger, Annekatrin Steinhoff, Amy Nivette, Aja L. Murray, Urs Hepp, Boris B. Quednow, Boris B. Quednow, Manuel P. Eisner, Manuel P. Eisner, Lilly Shanahan, Lilly Shanahan   +12 more
doaj   +1 more source

A Blueprint for Juvenile Justice Reform [PDF]

, 2006
Youth in the justice system are not so different from other youth that many foundations already serve. If your foundation supports youth development, education and after school programs, foster care, workforce development, or public health -- sectors ...

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Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial

Arthritis Care &Research, EarlyView.
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham, Thea Senger‐Carpenter, Jocelyn Zuckerman, Michelle Adler, Mallet R. Reid, Ashley Danguecan, Luana Flores Pereira, Sarah I. Mossad, Samantha L. Ely, Khalid Abulaban, Elizabeth A. Kessler, Natalie Rosenwasser, Tamar B. Rubinstein, Ekemini A. Ogbu, Emily A. Smitherman, Alaina Miller, Taylor Abounader, Elizabeth Ross, Livie Timmerman, Dhriti Sharma, Jennifer N. Stinson, Stacy Allen, Kabita Nanda, Tala El Tal, Deborah M. Levy, Linda T. Hiraki, Hermine I. Brunner, Mathew Reeves, Steven J. Pierce, Andrea Knight   +29 more
wiley   +1 more source

Reconceptualizing Youth Sparks: A Sociocultural Approach to CoDesigning Programs for Somali Youth

Journal of Human Sciences and Extension, 2022
The 4-H Youth Development Program has a long history of fostering positive youth outcomes. Recently, attention and resources have been invested in the development of a program model (i.e., the 4-H Thriving Model) that theorizes the program elements that ...
Joanna A. Tzenis
doaj   +1 more source

Our Voice Is Your Future: Giving L.A.'s Youth Real Voice and Real Power [PDF]

, 2004
Based on focus groups with youth and youth workers, identifies best practices and opportunities to engage youth in community-building.

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