Results 131 to 140 of about 457,497 (309)
Advanced Science, EarlyView.Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi +15 more
wiley +1 more source
Advanced Science, EarlyView.Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang +23 more
wiley +1 more source
The Faraday Scalpel: Electrochemical Nerve Lesioning Mechanisms Studied in Invertebrate Models
Advanced Science, EarlyView.Direct‐current produces nerve lesioning through discrete electrochemical reactions. Using hypoxia‐sensitive locust nerves and hypoxia‐tolerant leech nerves, we map three injury pathways: cathodic oxygen reduction, cathodic alkalization, and anodic chloride oxidation. These findings establish electrochemical lesioning—the “Faraday Scalpel”—as a precise,
Petra Ondráčková +5 more
wiley +1 more source
Performing performance: young aspiring athletes’ presentation of athletic identity
Frontiers in Sports and Active LivingYouths are in the process of figuring out answers to the question “who am I?” and young athletes are searching for athletic identity in interaction with their friends, teammates, coaches, and so on. This study explores athletes' presentations of athletic
Anette Skilbred +4 more
doaj +1 more source
Advanced Science, EarlyView.This paper proposes a hierarchical reconfigurable metasurface architecture (HRMA) to achieve comprehensive electromagnetic parameter modulation and on‐demand polymorphic function switching. The reconfigurable metasurface is divided into a programmable core (PC) and scenario‐guided functional modules (FMs), exhibiting significant flexibility and ...
Lihao Zhu +11 more
wiley +1 more source
Book Review: Fair Play: The Ethics of Sports
, 2011 During the past few years of my collegiate and youth-club coaching career, I have often found myself engrossed with many intellectual tasks in an attempt to improve both myself and my athletes\u27 chances for success.
Joseph, Dane C.
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Preserve birds in their natural NZ habitat and save their “Wild Musick”. [PDF]
, 2018 The Wild Musick framework has been created to support the Ministry of Business, Innovation and Employment (Tourism) NZ, Department of Conservation, Ministry of Conservation, and Ministry of Youth Development. It works to encourage the youth, and families
Ayesha, Hakim, Prashant, Khanna
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Advanced Science, EarlyView.A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li +6 more
wiley +1 more source
Faith, sport and disengaged youth [PDF]
, 2014 Set against a backdrop of faith-based explorations of sport with disengaged youth, the present paper presents findings from a project which sought to re-engage young people with sport via Christian youth ministry.
Collins, Mike F +2 more
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Advanced Science, EarlyView.The adsorption of AsV on akaganeite nanorods was found to provide a magnetic signature. A change in the surface spin order gave rise to a second peak in the zero‐field cooled curve. AsIII adsorption does not provide any change in the magnetic behavior of the sorbent.
Marco Sanna Angotzi +11 more
wiley +1 more source