Results 111 to 120 of about 30,759 (261)

Enriching Athlete-Environment Interactions in Youth Sport: The Role of a Department of Methodology. [PDF]

open access: yesChildren (Basel), 2023
Davids K   +4 more
europepmc   +1 more source

Self‐Sustaining Lactate Depletion Nanoplatform Remodels Tumor Microenvironment and Augments Synergistic Photodynamic/Photothermal/Chemodynamic/Starvation Therapy for Eradication of Colon Cancer

open access: yesAdvanced Science, EarlyView.
The HILA nanoplatform integrates HMnO2, LOX, and ICG to orchestrate multimodal therapy (starvation, chemodynamic, photodynamic, and photothermal) for achieving efficient colon cancer eradication. The established HMnO2‐LOX catalytic cycle continuously consumes lactate, acidifys microenvironment, relieves hypoxia, and generats reactive oxygen species ...
Yu‐E. Wang   +11 more
wiley   +1 more source

The social environment of talent development in youth sport. [PDF]

open access: yesFront Sports Act Living, 2023
Henriksen K, Stambulova N.
europepmc   +1 more source

Targeting NSUN2‐Mediated m5C Modification Attenuates Chondrocyte Senescence and NLRP3 Activation in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
NSUN2‐mediated m5C modification cooperates with ALYREF to stabilize and export IP3R3 mRNA, increasing IP3R3 expression and Ca2 + overload in chondrocytes. This signaling promotes mitochondrial dysfunction, NLRP3 inflammasome activation, and senescence, thereby accelerating osteoarthritis progression.
Guping Mao   +8 more
wiley   +1 more source

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

open access: yesAdvanced Science, EarlyView.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng   +20 more
wiley   +1 more source

Real‐Time Investigation of Interfacial Evolution in Electrochemical Energy Storage Systems via EQCM

open access: yesAdvanced Science, EarlyView.
Understanding the electrode/electrolyte interface (EEI) is crucial for supercapacitors and batteries. EQCM, by enabling real‐time monitoring of mass changes during charge–discharge cycles, has evolved into a vital method for analysis of EEI. It provides important insights into charge‐storage mechanisms, electrode structural evolution, ion‐transfer ...
Zixuan Wang, Situo Cheng, Guang Feng
wiley   +1 more source

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen   +8 more
wiley   +1 more source

ABCABC Stacking‐Enabled Non‐Centrosymmetry 3R‐ZnIn2S4 Nanosheets for Piezocatalytic Uranium Extraction

open access: yesAdvanced Science, EarlyView.
The ABCABC stacking sequence in 2D ZnIn2S4 nanosheets creates intrinsic non‐centrosymmetry, enabling robust piezocatalysis under weak mechanical agitation. The nanosheets achieve a H2O2 yield of 276.7 µmol g−1 h−1 and uranium extraction capacity of 763.2 mg g−1 via a dual mechanism of direct piezoreduction and in situ H2O2 complexation.
Song Li   +6 more
wiley   +1 more source

Kirigami‐Cut Pattern Designs for the Enhancement of Sensing Performance Induced by Programmable Out‐of‐Plane Deformation

open access: yesAdvanced Science, EarlyView.
Different kirigami patterns are proposed and the parameters are optimized by comparing the out‐of‐plane deformation behavior. Then, the proposed patterns are fabricated on PVDF film using laser technology. The deformed kirigami‐cut PVDF is embedded into PDMS to construct pressure senor.
Xiaodong Huang   +6 more
wiley   +1 more source

A Programmable Calcification Nanoplatform for Loco‐Regional Calcification‐Immune Hepatocellular Carcinoma Therapy

open access: yesAdvanced Science, EarlyView.
An in situ‐grown BP‐CaO2 nanoplatform supplies coordinated Ca2+, endogenous phosphate, and oxidative stress to convert tumor calcification from a passive endpoint into an active immune‐remodeling process. Widespread hydroxyapatite deposition is visualized by CT, while multi‐omics reveals MCOLN2 as a calcium‐responsive mediator linking biomineralization
Long Liu   +11 more
wiley   +1 more source

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