Results 61 to 70 of about 1,295,685 (397)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Purity and Danger – researching child protection and welfare in youth sport [PDF]

, 2006
Drawing on Mary Douglas’ classic social analysis in ‘Purity and Danger’ (1966) I argue that youth sport is a purity system and that pollution of it, through child abuse, breaches the belief system that still attaches to sport.
Brackenridge, CH
core  

The School Sport Co-ordinator Programme: Changing the Role of the Physical Education Teacher? [PDF]

, 2003
Over the last decade or so, young people have increasingly become a focus of UK sport policy. Fuelled in part by concerns such as the increasing levels of childhood inactivity and obesity, and the lack of international success in sport, a plethora of ...
Anne Flintoff, BALL S.J., BOWE R., BROWN D., CLAY G., COAKLEY J., DEPARTMENT FOR EDUCATION AND SCIENCE (DfES), DEPARTMENT OF CULTURE, MEDIA AND SPORT, DEPARTMENT OF EDUCATION AND SCIENCE, DEPARTMENT OF EDUCATION AND SCIENCE, EVANS J., EVANS J., EVANS J., EVANS J., FLINTOFF A., FLINTOFF A., GERTWITZ S., HARRIS J., HENDLEY K., MACDONALD D., MURDOCK L., PENNEY D., ROBSON S., ROWE N., SPARKES A., SPORT ENGLAND, VERMA G.   +26 more
core   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Empowering youth sport environments: Implications for daily moderate-to-vigorous physical activity and adiposity

Journal of Sport and Health Science, 2017
Background: Evidence suggests involvement in youth sport does not guarantee daily guidelines for moderate-to-vigorous physical activity (MVPA) are met, and participation may not mitigate the risks associated with physical inactivity.
Sally A.M. Fenton, Joan L. Duda, Paul R. Appleton, Timothy G. Barrett   +3 more
doaj   +1 more source

Emphasizing Sportsmanship in Youth Sport [PDF]

, 2016
This essay will examine the shift in cultural norms and social expectations surrounding youth sport and how emphases on sportsmanship in youth sport programs can help salvage some of the wholesome values sought after by parents when signing up their ...
Harrison, Todd
core   +1 more source

A longitudinal examination of coach and peer motivational climates in youth sport: Implications for moral attitudes, well-being, and behavioral investment. [PDF]

, 2012
Embedded in achievement goal theory (Ames, 1992; Meece, Anderman & Anderman, 2006), this study examined how perceptions of coach and peer motivational climate in youth sport predicted moral attitudes, emotional well-being, and indices of behavioral ...
Ntoumanis, Nikos, Taylor, Ian M., Thøgersen-Ntoumani, Cecilie   +2 more
core   +3 more sources

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

“You can definitely tell she's truly committed”: student-athletes’ discursive construction of athletic commitment during transitions in secondary school

Frontiers in Sports and Active Living
In this paper, we present how two female and one male student-athlete discursively construct and make sense of the “committed athlete”, highlighting key shifts across transitions between school levels and high-performance sport environments.
Marie Loka Øydna, Milla Saarinen, Jens Christian Nielsen, Christian Thue Bjørndal, Christian Thue Bjørndal   +4 more
doaj   +1 more source