Results 141 to 150 of about 834,251 (282)

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

open access: yesAdvanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol   +18 more
wiley   +1 more source

MOx/Rh Metallene with Energetic Interfaces as Efficient Bifunctional Electrocatalyst for Durable Water Splitting

open access: yesAdvanced Science, EarlyView.
 . ABSTRACT Developing excellent activity and stability bifunctional electrocatalysts for alkaline water splitting remains challenging. This work constructs ultrathin MOx/Rh metallene heterostructures (M = Fe, Co, Ni) via atmosphere‐controlled solvothermal synthesis, achieving uniform MOx nanoclusters on Rh metallene with optimized interfaces. The FeOx/
Ruilong Wei   +10 more
wiley   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

open access: yesAdvanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang   +16 more
wiley   +1 more source

Challenges in Transitioning Single-Stream Colleges into Multidisciplinary Institutions Under NEP 2020

open access: yesThe Achievers Journal: Journal of English Language, Literature and Culture
The transition of single-stream colleges into multidisciplinary institutions, as envisioned under NEP 2020, marks a transformative shift in India's higher education landscape.
Gurpal Singh Rana
doaj  

Ys Marianas [Mapa]

open access: yes
Orientado con media lis Aparecen las Islas Saypan y Finian con fondeaderos y veriles, dibujadas amodo de croquis y de forma muy simple Copia digital. Madrid : Ministerio de Cultura.
openaire   +1 more source

YS Arbeidslivsbarometer: Norsk arbeidsliv 2014

open access: yes, 2014
YS Arbeidslivsbarometer er gjennomført for 6. gang. Rapporten som ble lagt fram på YS-konferansen er bygd opp rundt fem temaområder. Disse er valgt ut fordi de er sentrale for å forstå utviklingen av norsk arbeidsliv, sett fra arbeidstakeres perspektiv.
Bergene, Ann Cecilie   +2 more
openaire   +2 more sources

DCAF13 Safeguards Hematopoietic Stem Cells via RRS1‐Regulated Ribosome Biogenesis

open access: yesAdvanced Science, EarlyView.
This study establishes DCAF13 as an essential regulator for hematopoietic stem cell (HSC) function. Its deletion in mice causes lethal pancytopenia and HSC depletion. Mechanistically, DCAF13 interacts with RRS1 and mediates its non‐degradative K27‐linked ubiquitination, thereby stabilizing RRS1 to maintain ribosome biogenesis and protein translation ...
Mengke Li   +25 more
wiley   +1 more source

Correction: Tracking early mammalian organogenesis - prediction and validation of differentiation trajectories at whole organism scale. [PDF]

open access: yesDevelopment
Imaz-Rosshandler I   +12 more
europepmc   +1 more source

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