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Treatment planning for molecular radiotherapy: potential and prospects [PDF]

, 2017
Aldridge, Matt, Bacher, Klaus, Brans, Boudewijn, Chiesa, Carlo, Cicone, Francesco, Gabina, Pablo Minguez, Gleisner, Katarina Sjogreen, Kobe, Carsten, Konijnenberg, Mark, Paphiti, Maria, Sandstrom, Mattias, Solny, Pavel, Spezi, Emiliano, Tipping, Jill, Wissmeyer, Michael   +14 more
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Yttrium-90 Radioembolization: Current Indications and Outcomes

Journal of Gastrointestinal Surgery, 2023
Radioembolization (RE) with 90Yttrium (Y90) has generally been used to treat patients with advanced disease. Recent data suggest, however, that RE is also safe and feasible to treat patients with early or intermediate stage disease. We herein review the current evidence regarding the use of RE with Y90 for patients with HCC.A comprehensive review of ...
Ahmad Hamad, Hassan Aziz, Ihab R. Kamel, Dayssy Alexandra Diaz, Timothy M. Pawlik   +4 more
openaire   +2 more sources

Abscopal Effects and Yttrium-90 Radioembolization

CardioVascular and Interventional Radiology, 2015
We present the case of an 80-year-old male with squamous cell carcinoma with bilobar hepatic metastases who underwent targeted Yttrium-90 radioembolization of the right hepatic lobe lesion. Subsequently, there was complete regression of the nontargeted, left hepatic lobe lesion.
Anish, Ghodadra, Sumantha, Bhatt, Juan C, Camacho, Hyun S, Kim   +3 more
openaire   +2 more sources

Yttrium-90 Radioembolization for Hepatocellular Carcinoma

Seminars in Nuclear Medicine, 2016
(90)Y radioembolization refers to the selective, transcatheter, and intra-arterial injection of micrometer-sized particles loaded with the radioisotope yttrium-90 for the treatment of primary and metastatic hepatic malignancies. In the treatment of intermediate- and advanced-stage hepatocellular carcinoma, (90)Y radioembolization provides favorable ...
Ryan M, Hickey, Robert J, Lewandowski, Riad, Salem   +2 more
openaire   +2 more sources

Safety of Repeated Yttrium-90 Radioembolization

CardioVascular and Interventional Radiology, 2013
Repeated radioembolization (RE) treatments carry theoretically higher risk of radiation-induced hepatic injury because of the liver's cumulative memory of previous exposure. We performed a retrospective safety analysis on patients who underwent repeated RE.From 2004 to 2011, a total of 247 patients were treated by RE.
Marnix G E H, Lam, John D, Louie, Andrei H, Iagaru, Michael L, Goris, Daniel Y, Sze   +4 more
openaire   +2 more sources

Yttrium-90 microsphere radioembolization in unresectable intrahepatic cholangiocarcinoma

Future Oncology, 2017
Intrahepatic cholangiocarcinoma is increasing in frequency worldwide, but radical surgical treatment is practicable in 30-40% of cases. The median survival without therapy is about 8 months, increased to 12 months in combination with systemic chemotherapy.
Mosconi, Cristina, Cappelli, Alberta, Ascanio, Salvatore, Pettinari, Irene, Modestino, Francesco, Renzulli, Matteo, Galaverni, Maria Cristina, Cucchetti, Alessandro, Gramenzi, Annagiulia, Pettinato, Cinzia, Golfieri, Rita   +10 more
openaire   +2 more sources

Yttrium-90 Radioembolization in the Office-Based Lab

Journal of Vascular and Interventional Radiology, 2020
To evaluate the feasibility and benefits of performing yttrium-90 radioembolization in an office-based lab (OBL) compared to a hospital setting.A radioembolization program was established in March 2019 in an OBL that is managed by the radiology department of a tertiary care center.
Ryan M, Hickey, John M, Maslowski, Eric T, Aaltonen, Jeremy Cash, Horn, Amish, Patel, Akhilesh K, Sista, Jonathan S, Gross   +6 more
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Liver abscess following radioembolization with yttrium-90 microspheres

Wiener klinische Wochenschrift, 2014
Radioembolization with yttrium-90 microspheres is an accepted and useful intervention model with minimal invasion in both primary and secondary liver malignancies. Radioembolization may lead to some complications. Liver abscess is a rare complication that can occur several weeks after radioembolization treatment of liver tumor with yttrium-90 ...
Bozkaya, Halil, Korkmaz, Mehmet, Cinar, Celal, Sanal, Bekir, Guneyli, Serkan, Parildar, Mustafa, Oran, Ismail   +6 more
openaire   +5 more sources

Radioembolization of Liver Tumors With Yttrium-90 Microspheres

Seminars in Nuclear Medicine, 2010
Radioembolization (RE), also termed selective internal radiation therapy (SIRT), has been gradually introduced to the clinical arsenal of cytoreductive modalities in recent years. There is growing evidence for efficiency in liver tumors of various entities, with the most prominent ones being hepatocellular carcinoma, colorectal cancer, and ...
Hojjat, Ahmadzadehfar, Hans-Jürgen, Biersack, Samer, Ezziddin   +2 more
openaire   +2 more sources

Splenomegaly-Associated Thrombocytopenia After Hepatic Yttrium-90 Radioembolization

CardioVascular and Interventional Radiology, 2013
Thrombocytopenia is often observed after yttrium-90 radioembolization (RE). Possible mechanisms include radiation toxicity to the bone marrow, consumption in the liver due to local radiation effects, and sequestration in the spleen. We sought to identify the causative factors.Patients with complete baseline and 3-month post-RE imaging and laboratory ...
Marnix G E H, Lam, Arjun, Banerjee, John D, Louie, Daniel Y, Sze   +3 more
openaire   +2 more sources