Results 91 to 100 of about 782,973 (259)

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

open access: yesAdvanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao   +28 more
wiley   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

open access: yesAdvanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu   +14 more
wiley   +1 more source

Dual Cytoplasmic and Chloroplastic Mechanisms Fine‐Tune Chloroplast Division through ARC3 Protein Stability

open access: yesAdvanced Science, EarlyView.
ARC3 levels are controlled by cytosolic and chloroplast proteolytic systems. PUB52 mediates ARC3 precursor ubiquitination and degradation in the cytosol, while CLPC1 promotes ARC3 degradation in chloroplasts, where ARC2 protects ARC3 from excessive breakdown. Disrupting these components causes chloroplast division defects, placing them upstream of ARC3.
Yang Yuan   +5 more
wiley   +1 more source

Late Neoarchean magmatism and crustal growth in northern Liaoning: evidence from zircon U-Pb geochronology and petro-geochemistry of the Qingyuan trondhjemites

open access: yes
Data accompanying " Late Neoarchean magmatism and crustal growth in northern Liaoning: evidence from zircon U-Pb geochronology and petro-geochemistry of the Qingyuan trondhjemites" by LL Yuan, J Liu, XH Zhang, ZL Yang, H Zhang, HB Li ...
Yuan, L
core   +1 more source

Epigenetic Silencing of RFX7 Defines a Transcriptional Axis Linking Lactate Metabolism to Immune Checkpoint Therapy in Glioblastoma

open access: yesAdvanced Science, EarlyView.
Glioblastoma (GBM) exhibits RFX7 silencing via promoter hypermethylation, which downregulates PIK3IP1 to activate PI3K/AKT signaling, increase lactate accumulation, and enhance histone H4K12 lactylation. This lactylation upregulates PD‐L1/CSF1 expression and drives the immunosuppressive microenvironment formation.
Liying Han   +20 more
wiley   +1 more source

Oral Motion‐Powered Smart Dental Implant Abutment for In Situ Antibacterial and Cell Adhesion Through Piezoelectric Effect

open access: yesAdvanced Science, EarlyView.
We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi   +15 more
wiley   +1 more source

Xiang zhu Sui yuan nü di zi shi xuan

open access: yes, 1929
袁枚選 ; 增註者謝璿].Yuan Mei xuan ; zeng zhu zhe Xie Xuan]

core  

Introgressed Variation in TaMYB7‐A1 Drives Graded Dormancy and Climate‐Adaptive Pre‐Harvest Sprouting Resistance in Wheat

open access: yesAdvanced Science, EarlyView.
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang   +18 more
wiley   +1 more source

Jiang xue yuan de yi ben cao

open access: yes
V.1. 條目 -- 絳雪園得宜本草 / 王晉三集 ; 吳蒙校 -- 絳雪園古方選註 : 六門 : 和劑四十四方 / 王子接註 ; 葉桂校 -- v.2. 絳雪園古方選註 : 寒劑十方 / 王子接註 ; 薛雪校 -- 温劑十九方 / 王子接註 ; 葉桂校 -- 汗劑十三方 / 王子接註 ; 葉桂校 -- 吐劑五方 / 王子接註 ; 王士琳校 -- 下劑二十二方 / 王子接註 ; 葉桂校 -- v.3-4. 絳雪園古方選註 : 內科 / 王子接註 ; 葉桂校 -- v.5. 絳雪園古方選註 : 內科丸方 /

core  

Dataset for: Superoscillatory quartz lens with numerical aperture greater than one

open access: yes
Dataset with supporting data for paper: Zheludev, N, Yuan, GH, Tsai, DP & Lin, Y-H 2020, 'Superoscillatory quartz lens with numerical aperture greater than one' Applied Physics Letters.
Yuan, Guanghui, Zheludev, Nikolai
core   +1 more source

Home - About - Disclaimer - Privacy