Results 121 to 130 of about 1,061,367 (275)

Frequency Variation of the Kilohertz Quasi-periodic Oscillations and the Flux of the Band-limited Noise in Scorpius X-1

, 2008
We study the kilohertz quasi-periodic oscillations (kHz QPOs) and the band-limited noise (BLN) in the 0.5--16 Hz range observed simultaneously on the horizontal branch (HB) and on the upper normal branch (NB) of the brightest neutron star Low-mass X-ray ...
Alpar, Belloni, Bradt, Di Salvo, Ford, Hasinger, Homan, Homan, Horák, Jonker, Kaaret, Kuulkers, Kuulkers, Lai, Lamb, Lewin, Li, Miller, Méndez, Psaltis, Shirakawa, Stella, Titarchuk, Titarchuk, Titarchuk, van der Klis, van der Klis, van der Klis, van der Klis, van-der Klis, Wenfei Yu, Wijnands, Wijnands, Xiaofeng Cao, Yu, Yu, Yu, Yu   +37 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

The rms-flux relations in different branches in Cyg X-2

, 2012
In this paper, the rms-flux (root mean square-flux) relation along the Z-track of the bright Z-Source Cyg X-2 is analyzed using the observational data of Rossi X-ray Timing Explorer (RXTE). Three types of rms-flux relations, i.e. positive, negative, and '
A.P. Cowley, C. M. Zhang, E. Kuulkers, E. Kuulkers, G. Hasinger, G. Hasinger, H.V. Bradt, I.M. McHardy, J. Casares, J. L. Qu, J. Y. Nie, J.A. Orosz, K. Mitsuda, L. M. Song, L.M. Heil, L.M. Heil, M. Klis van der, M. Klis van der, M. Klis van der, M.A. Nowak, M.J. Church, M.J. Church, N.E. White, P. Uttley, P. Uttley, P. Uttley, R. Misra, R. Wijnands, R.A.D. Wijnands, R.E. Shirey, S. Miyamoto, S. Piraino, S. Vaughan, S.M. Kahn, S.N. Zhang, T. Di Salvo, T. Gleissner, W. Zhang, Y. J. Lei, Y.E. Lyubarskii, Y.J. Lei, Z. B. Li, Z.B. Li   +42 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

A common-ground switched-capacitor multilevel inverter with extended input range for renewable energy applications

International Journal of Electrical Power & Energy Systems
Multilevel inverters (MLIs) have emerged as a prominent front-end converter solution for renewable energy generation like photovoltaic (PV), fuel cell and wind turbine, owing to their low total harmonic distortion (THD) and high conversion efficiency ...
Zaiyu Chen, Minghui Yin, Jia Yao, Guoliang Liu, Qun Li, Qiang Li   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Switched-Inductor Extended-Boost Quasi-Z-Source Inverter

IEEE Access
This paper introduces two novel impedance source inverter topologies for switched-inductor extended-boost quasi-Z-source inverters: diode-assisted and capacitor-assisted switched-inductor extended-boost quasi-Z-source inverters.
Abhishek Paikray, Dezi Shrivastav, Sisir Kumar Nayak   +2 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Controlling Both the DC Boost and AC Output Voltage of Z-Source Inverter Using Neural Network Controller with Minimization of Voltage Stress Across Devices

Iranian Journal of Electrical and Electronic Engineering, 2011
This paper presents a method to control both the dc boost and the ac output voltage of Z-source inverter using neural network controllers. The capacitor voltage of Z-source network has been controlled linearly in order to improve the transient response ...
D. Arab Khaburi, H. Rostami
doaj