Results 231 to 240 of about 1,095,227 (294)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Untargeted Multiple Reaction Monitoring. [PDF]

Anal Chem
Uritboonthai W, Aisporna A, Hoang L, Webb B, Billings EM, Hoang C, Tobea M, Cates-Gatto CC, Roberts AJ, Teav T, Borreggine R, Kyritsi I, Gallart-Ayala H, Ivanisevic J, Popova A, Williamson JR, Plumb R, Siuzdak G.   +17 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Comparative genome analysis provides a foundation for defining salvinorin A biosynthesis in Salvia divinorum. [PDF]

Nat Commun
Li H, Sun Y, Xu W, Sun B, Wu S, Li C, Zhao J, Martin C, Tatsis EC.   +8 more
europepmc   +1 more source

[Corrigendum] Macrophage‑derived foam cells impair endothelial barrier function by inducing endothelial‑mesenchymal transition via CCL‑4. [PDF]

Int J Mol Med
Yang Y, Luo NS, Ying R, Xie Y, Chen JY, Wang XQ, Gu ZJ, Mai JT, Liu WH, Wu MX, Chen ZT, Fang YB, Zhang HF, Zuo ZY, Wang JF, Chen YX.   +15 more
europepmc   +1 more source

An X-ray-emitting protocluster at z ≈ 5.7 reveals rapid structure growth. [PDF]

Nature
Bogdán Á, Schellenberger G, Li Q, Conselice CJ.   +3 more
europepmc   +1 more source

Identification and Geochemical Significance of Novel <i>des</i>-A-Triterpenoids and Mononuclear-Aromatic <i>des</i>-A-Triterpenoids in Tertiary Terrestrial Oils from the Northern of the South China Sea. [PDF]

ACS Omega
Ran Z, Li M, Xiao H, Gao Z, Yuan M, Dong S, Zhang J, Zhao Q, Chen H.   +8 more
europepmc   +1 more source

Loss of ZNRF3/RNF43 unleashes EGFR in cancer. [PDF]

Elife
Yue F, Ku AT, Stevens PD, Michalski MN, Jiang W, Tu J, Shi Z, Dou Y, Wang Y, Feng XH, Hostetter G, Wu X, Huang S, Shroyer NF, Zhang B, Williams BO, Liu Q, Lin X, Li Y.   +18 more
europepmc   +1 more source