Results 31 to 40 of about 164,290 (263)

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A novel ensemble regressor and causal analysis for predicting the compressive strength of steel fiber-reinforced concrete

Ain Shams Engineering Journal
Steel fiber reinforced concrete incorporating supplementary materials offers improved toughness and durability, yet its compressive strength remains difficult to forecast because performance emerges from coupled effects of mixture composition, fiber ...
Aybike Özyüksel Çiftçioğlu, Murteda Unverdi, Naz Mardani, Ali Mardani   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Heuristic Search for the Analysis of Graph Transition Systems

, 2006
Graphs are suitable modeling formalisms for software and hardware systems involving aspects such as communication, object orientation, concurrency, mobility and distribution.
Lluch-Lafuente, Alberto, Jabbar, Shahid, Edelkamp, Stefan, Alberto Lluch Lafuente, Shahid Jabbar, Stefan Edelkamp   +5 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

An 00 visual language definition approach supporting multiple views [PDF]

, 2000
The formal approach to visual language definition is to use graph grammars and/or graph transformation techniques. These techniques focus on specifying the syntax and manipulation rules of the concrete representation. This paper presents a constraint and
I.E.E.E. Computer Society, Akehurst, David H.   +1 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Complex hierarchical structures analysis in single-cell data with Poincaré deep manifold transformation

Briefings Bioinform.
Single-cell RNA sequencing (scRNA-seq) offers remarkable insights into cellular development and differentiation by capturing the gene expression profiles of individual cells. The role of dimensionality reduction and visualization in the interpretation of
Yongjie Xu, Zelin Zang, Bozhen Hu, Yue Yuan, Cheng Tan, Jun Xia, Stan Z. Li   +6 more
semanticscholar   +1 more source

Transformation As Search [PDF]

, 2013
In model-driven engineering, model transformations are con- sidered a key element to generate and maintain consistency between re- lated models. Rule-based approaches have become a mature technology and are widely used in different application domains ...
Marcos Didonet Del Fabro, Davi De Queiroz Santos, DE QUEIROZ SANTOS, Davi, KLEINER, Mathias, DIDONET DEL FABRO, Marcos, Mathias Kleiner   +5 more
core   +1 more source