Results 131 to 140 of about 8,621,823 (240)
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Zaburzenia lipidowe u pacjentów z zawrotami głowy
Wprowadzenie: Celem pracy była ocena zaburzeń lipidowych u pacjentów z zawrotami głowy. Materiał i metody: Badania przeprowadzono na grupie 918 chorych, w tym 598 kobiet i 320 mężczyzn, w wieku 18–83 lat (średnia wieku 55±0,5), leczonych w latach 2009 ...
Jurek Olszewski +4 more
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Peptoids are peptide-mimicking polymers. In theory, a charged peptoid backbone can break into small fragments systemically following chemical bonds.
Adlakha, Ankit
core
The global impact of physical activity and physical exercise on body mass index (BMI) and waist circumference (WC) in people with Intellectual and Developmental Disabilities (IDD), is not known, nor is the most effective type of exercise training for ...
Miguel Jacinto +5 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Experiences using Z animation tools. [PDF]
In this paper we describe our experience of using three different animation systems. We searched for and decided to use these tools in the context of a project which involved developing formal versions (in Z) of informal requirements documents, and then ...
Reeves, Steve, Reeve, Greg
core
The reference change value (RCV), also known as the critical difference, can be defined as the smallest difference required before two sequential laboratory results are considered significantly different (at a predefined confidence level), after taking ...
Loh, Tze Ping +3 more
core +1 more source
Generation Z is known for frequently moving from one company to another. This is related to how Generation Z employees commit to their jobs both emotionally and intellectually within an organization or company.
Restiani Restiani, Ira Puspitawati
doaj +1 more source

