Results 131 to 140 of about 8,621,823 (240)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Zaburzenia lipidowe u pacjentów z zawrotami głowy

open access: yes, 2012
Wprowadzenie: Celem pracy była ocena zaburzeń lipidowych u pacjentów z zawrotami głowy. Materiał i metody: Badania przeprowadzono na grupie 918 chorych, w tym 598 kobiet i 320 mężczyzn, w wieku 18–83 lat (średnia wieku 55±0,5), leczonych w latach 2009 ...
Jurek Olszewski   +4 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

M/Z Value Calculator

open access: yes, 2014
Peptoids are peptide-mimicking polymers. In theory, a charged peptoid backbone can break into small fragments systemically following chemical bonds.
Adlakha, Ankit
core  

Impact of exercise programs on body mass index and waist circumference of individuals with Intellectual and Developmental Disabilities: a systematic review with meta-analysis

open access: yesMotricidade
The global impact of physical activity and physical exercise on body mass index (BMI) and waist circumference (WC) in people with Intellectual and Developmental Disabilities (IDD), is not known, nor is the most effective type of exercise training for ...
Miguel Jacinto   +5 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Experiences using Z animation tools. [PDF]

open access: yes, 2001
In this paper we describe our experience of using three different animation systems. We searched for and decided to use these tools in the context of a project which involved developing formal versions (in Z) of informal requirements documents, and then ...
Reeves, Steve, Reeve, Greg
core  

A simple approach to derive Z-score of reference change value involving more than two serial results (Letter)

open access: yes, 2015
The reference change value (RCV), also known as the critical difference, can be defined as the smallest difference required before two sequential laboratory results are considered significantly different (at a predefined confidence level), after taking ...
Loh, Tze Ping   +3 more
core   +1 more source

Pengaruh Transformational Leadership dan Psychological Capital terhadap Work Engagement pada Karyawan Generasi Z

open access: yesJurnal Ilmu Perilaku
Generation Z is known for frequently moving from one company to another. This is related to how Generation Z employees commit to their jobs both emotionally and intellectually within an organization or company.
Restiani Restiani, Ira Puspitawati
doaj   +1 more source

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