Results 141 to 150 of about 10,467,681 (290)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

An infinitesimal model for quantitative trait genomic value prediction

open access: yes, 2012
We developed a marker based infinitesimal model for quantitative trait analysis. In contrast to the classical infinitesimal model, we now have new information about the segregation of every individual locus of the entire genome.
Xu, S., Hu, Z., Wang, Z.
core   +1 more source

Pengaruh Transformational Leadership dan Psychological Capital terhadap Work Engagement pada Karyawan Generasi Z

open access: yesJurnal Ilmu Perilaku
Generation Z is known for frequently moving from one company to another. This is related to how Generation Z employees commit to their jobs both emotionally and intellectually within an organization or company.
Restiani Restiani, Ira Puspitawati
doaj   +1 more source

Generation Z Value Preferences And Their Sociocultural Determinants

open access: yesEuropean Proceedings of Social and Behavioural Sciences, 2020
Mikhail Sergeyevich Yanitskiy   +2 more
openaire   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

z-haiman/RBC-GEM: RBC-GEM 1.0.0

open access: yes
<p>First major release of RBC-GEM, changes will be outlined in upcoming manuscript!</p> <p><strong>Full Changelog</strong>: https://github.com/z-haiman/RBC-GEM/compare/0.3.0...1.0.0</p ...
z-haiman
core   +1 more source

Dietoterapia doustna u pacjentów z anoreksją

open access: yes, 2016
Anorexia nervosa jest polietiologicznym specyficznym zaburzeniem odżywiania, którego objawy i powikłania mają charakter psychologiczny, społeczny i somatyczny.
Agata Dutkiewicz, Teresa Grzelak
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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