Results 141 to 150 of about 8,621,823 (240)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An infinitesimal model for quantitative trait genomic value prediction

, 2012
We developed a marker based infinitesimal model for quantitative trait analysis. In contrast to the classical infinitesimal model, we now have new information about the segregation of every individual locus of the entire genome.
Xu, S., Hu, Z., Wang, Z.
core   +1 more source

Understand the Chinese Z Generation consumers’ Green hotel visit intention: An Extended Theory of Planned Behavior Model

Heliyon
In the context of growing environmental concerns and a shift towards sustainable tourism, understanding the behaviors of younger generations, particularly Generation Z, becomes crucial for the hotel industry.
Haodong Wu, Weizheng Wang, Yinying Tao, Ming Shao, Chenwei Yu   +4 more
doaj   +1 more source

Generation Z Value Preferences And Their Sociocultural Determinants

European Proceedings of Social and Behavioural Sciences, 2020
Mikhail Sergeyevich Yanitskiy, Andrey Victorovich Seryy, Olga Arturovna Braun   +2 more
openaire   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

z-haiman/RBC-GEM: RBC-GEM 1.0.0

<p>First major release of RBC-GEM, changes will be outlined in upcoming manuscript!</p> <p><strong>Full Changelog</strong>: https://github.com/z-haiman/RBC-GEM/compare/0.3.0...1.0.0</p ...
z-haiman
core   +1 more source

Dietoterapia doustna u pacjentów z anoreksją

, 2016
Anorexia nervosa jest polietiologicznym specyficznym zaburzeniem odżywiania, którego objawy i powikłania mają charakter psychologiczny, społeczny i somatyczny.
Agata Dutkiewicz, Teresa Grzelak
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Powikłania neurologiczne współistniejące z niewydolnością nerek

, 2010
Powikłania neurologiczne w przebiegu niewydolności nerek, zarówno te spowodowane mocznicą, jak i wynikające z jej leczenia, dotyczą ośrodkowego oraz obwodowego układu nerwowego, jak również tkanki mięśniowej i stanowią przyczynę zwiększonej śmiertelności
Maria Łukasik
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source