Results 231 to 240 of about 3,718,179 (297)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

What Does Next-Generation Mass Spectrometry Offer for Proteomics? A Comprehensive Platform Comparison. [PDF]

J Proteome Res
Blasco Tavares Pereira Lopes F, Schlatzer D, Sudhadevi T, Harijith A, Ayati M, Koyutürk M, Chance MR.   +6 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Differences in Sports Learning by Digital Literacy Level Among Generation Z: An Application of the Unified Theory of Acceptance and Use of Technology (UTAUT) and Media Richness Theory (MRT). [PDF]

Behav Sci (Basel)
Jeong KH, Choi C, Mun H.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

An unbiased comparison of 14 epigenetic clocks in relation to 174 incident disease outcomes. [PDF]

Nat Commun
Mavrommatis C, Belsky DW, Ying K, Moqri M, Campbell A, Richmond A, Gladyshev VN, Chandra T, McCartney DL, Marioni RE.   +9 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Blood-based DNA methylation captures variance in adult height. [PDF]

Genome Biol
Hatton AA, Hillary RF, McCartney DL, Harris SE, Cox SR, Evans KL, Walker RM, Suderman M, Yousefi P, McRae AF, Marioni RE.   +10 more
europepmc   +1 more source

<i>RBFOX1</i> Dysfunction Unlocks <i>APOE4</i>-Associated Microglial Genesis and Exacerbates Alzheimer's Pathology in Human Cerebral Organoids. [PDF]

Exploration (Beijing)
Zhang B, Shi C, Zhao J, Hua Q, Zhang H, Gao H, Qian Y, Cha J, Li J, Chen J, Kim TH, Xue J, Hou Y, Zhang R.   +13 more
europepmc   +1 more source