Results 81 to 90 of about 3,718,179 (297)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Impact Factors and Mechanisms of University Graduates' Reverse Mobilities amid China's Social Transformation

open access: yesRedai dili
Social changes have triggered a drive for change among young people, leading to a spatial reverse mobility trend among university graduates in China, amid shifts in both domestic and international contexts.
Luo Jiawei   +3 more
doaj   +1 more source

Generation Z and Learning Styles [PDF]

open access: yesSSRN Electronic Journal, 2019
Due to technological evolution and digitalization education has encountered many changes in the last decade. Students as a part of educational system bring their own footprint on it through their learning styles. Therefore, the aim of this study is to evaluate the learning styles of a group of undergraduate and postgraduate students. The achievement of
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Beyond Risk: How the Z Generation Resist the Temptation of Online Games

open access: yesSoshum: Jurnal Sosial dan Humaniora
The increasing prevalence of online gaming has raised concerns about potential challenges facing students, particularly regarding mental health, financial stability, and economic implications.
Sri Ayu Evianti, Dien Vidia Rosa
doaj   +1 more source

Quartic Anomalous Couplings in $\gamma\gamma$ Colliders

open access: yes, 1995
We study the constraints on the vertices $W^+W^- Z\gamma$, $W^+W^-\gamma\gamma$, and $ZZ\gamma\gamma$ that can be obtained from triple-gauge-boson production at the next generation of linear $e^+e^-$ colliders operating in the $\gamma\gamma$ mode.
A. Hill   +24 more
core   +1 more source

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