Results 81 to 90 of about 821,224 (305)

Impact Factors and Mechanisms of University Graduates' Reverse Mobilities amid China's Social Transformation

Redai dili
Social changes have triggered a drive for change among young people, leading to a spatial reverse mobility trend among university graduates in China, amid shifts in both domestic and international contexts.
Luo Jiawei, Ma Ling, Chen Jiahao, Wang Haifeng   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Beyond Risk: How the Z Generation Resist the Temptation of Online Games

Soshum: Jurnal Sosial dan Humaniora
The increasing prevalence of online gaming has raised concerns about potential challenges facing students, particularly regarding mental health, financial stability, and economic implications.
Sri Ayu Evianti, Dien Vidia Rosa
doaj   +1 more source

Generation Z and sports brands [PDF]

, 2021
Title: Generation Z and sports brands Objectives: Main goal of the diploma thesis is to find out brand importance in decision-making process of generation Z living in capital city of Prague using group interviews. Methods: The qualitative method was used
Šustrová, Tereza
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Generation Z employees

, 2023
Born between the years 1995 and 2010, Generation Z employees grow up with several characteristics, such as preferring flexible work patterns, valuing salary, benefits, job security, and workplace happiness (Chillakuri, 2020; Ivasciuc et al., 2022). These
Pratista Arya Satwika
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Ternary Triazole-Based Organic–Inorganic Proton-Conducting Hybrids Based on Computational Models for HT-PEMFC Application

ACS Omega, 2023
Towa Bunno, Keiichiro Maegawa, Mateusz Wlazło, Kazuhiro Hikima, Atsushi Nagai, Atsunori Matsuda   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source