Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Genome-based reclassification of <i>Alkalispirochaeta sphaeroplastigenens</i> (Vishnuvardhan Reddy <i>et al</i>. 2013) Sravanthi <i>et al</i>. 2016 as a later heterotypic synonym of <i>Alkalispirochaeta alkalica</i> (Zhilina <i>et al</i>. 1996) Sravanthi <i>et al</i>. 2016. [PDF]
Scranton MM +4 more
europepmc +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Influence of Food Environment Around Schools on Nutritional Status and Body Mass Index Trajectories Among Children and Adolescents. [PDF]
Lian X +17 more
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Iontronics of nanofluidic conical pores: learning phenomena using voltage pulses.
Portillo S +5 more
europepmc +1 more source
Batch correction for large-scale mass spectrometry imaging experiments. [PDF]
Sparre AA, Jensen ON.
europepmc +1 more source
Longitudinal Spinal Cord Atrophy in Patients With Neuromyelitis Optica Spectrum Disorder and Its Association With Rituximab Treatment. [PDF]
Yao Y +16 more
europepmc +1 more source
Antioxidant and Neuroprotective Effects of 20% Marigold Extract Oil (Lutein/Zeaxanthin Complex) in LED-induced Retinal Injury and A2E-mediated ARPE-19 Models. [PDF]
Kim YH +5 more
europepmc +1 more source

