Results 41 to 50 of about 725 (155)

Frequency and Early Predictors of Cognitive Deterioration in Amyotrophic Lateral Sclerosis: A Longitudinal Population‐Based Study

Annals of Neurology, Volume 97, Issue 6, Page 1122-1133, June 2025.
Objective The objective is to evaluate cognitive and behavioral progression and identify early predictors of these changes in a cohort of amyotrophic lateral sclerosis (ALS) patients. Methods A total of 161 ALS patients were tested at diagnosis (T0), and 107 were re‐tested after 1 year (T1) using cognitive/behavioral tests. All patients underwent whole‐
Barbara Iazzolino, Francesca Palumbo, Cristina Moglia, Umberto Manera, Maurizio Grassano, Enrico Matteoni, Sara Cabras, Maura Brunetti, Rosario Vasta, Marco Pagani, Gabriele Mora, Antonio Canosa, Andrea Calvo, Adriano Chiò   +13 more
wiley   +1 more source

Otyłość - ważny problem zdrowotny

Studia Ecologiae et Bioethicae, 2005
Obesity affecting more than 30% of adult population has been recognized as a major public health problem. Overweight and obesity generally are caused by unhealthy eating patterns and a lack of physical activity.
Grażyna Nowicka
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Decyzje GIF w zakresie reklamy produktu leczniczego jako instrument ochrony zdrowia. Między wolnością wypowiedzi, wolnością działalności gospodarczej a odpowiedzialnością za zdrowie

Acta Universitatis Lodziensis Folia Iuridica, 2023
Troska o zdrowie człowieka jest jednym z zadań administracji publicznej w jej misji na rzecz dobra wspólnego. Organem, któremu powierzono część zadań z tego zakresu, jest Główny Inspektor Farmaceutyczny (GIF)/the Chief Pharmaceutical Inspector.
Lidia K. Jaskuła
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Site‐Specific Modification of Native IgGs with Flexible Drug‐Load

ChemBioChem, Volume 26, Issue 8, April 14, 2025.
ADC generation from native IgG: using short, positively charged peptides like RAK enables the direct modification of IgG at the glutamine Q295 without the need for engineering. Using azide‐ and thiol‐group containing RAK, the generation of ADCs with different drug‐to‐antibody ratios (DARs) is demonstrated and their properties analyzed in‐vitro and in ...
Jöri E. Wehrmüller, Julia C. Frei, Torsten Hechler, Michael Kulke, Andreas Pahl, Martin Béhé, Roger Schibli, Philipp R. Spycher   +7 more
wiley   +1 more source

High Frequency of Cognitive and Behavioral Impairment in Amyotrophic Lateral Sclerosis Patients with SOD1 Pathogenic Variants

Annals of Neurology, Volume 96, Issue 1, Page 150-158, July 2024.
Objective While the cognitive‐behavioral characteristics of amyotrophic lateral sclerosis (ALS) patients carrying C9orf72 pathological repeat expansion have been extensively studied, our understanding of those carrying SOD1 variants is mostly based on case reports. The aim of this paper is to extensively explore the cognitive‐behavioral characteristics
Andrea Calvo, Cristina Moglia, Antonio Canosa, Umberto Manera, Rosario Vasta, Maurizio Grassano, Margherita Daviddi, Filippo De Mattei, Enrico Matteoni, Salvatore Gallone, Maura Brunetti, Luca Sbaiz, Sara Cabras, Laura Peotta, Francesca Palumbo, Barbara Iazzolino, Gabriele Mora, Adriano Chiò   +17 more
wiley   +1 more source

Niekorzystne oddziaływanie komputera na zdrowie człowieka w wymiarze holistycznym

Horyzonty Wychowania, 2009
Nadmierne i niekontrolowane korzystanie z komputera i Internetu może negatywnie oddziaływać na zdrowie człowieka w jego wymiarze holistycznym. Nieprawidłowo używany sprzęt może nieść z sobą poważne konsekwencje zdrowotne, dlatego należy rozpatrywać je ...
Anna Potocka
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Evaluation of critical parameters in the hollow‐fibre system for tuberculosis: A case study of moxifloxacin

British Journal of Clinical Pharmacology, Volume 90, Issue 7, Page 1711-1727, July 2024.
Aims The hollow‐fibre system for tuberculosis (HFS‐TB) is a preclinical model qualified by the European Medicines Agency to underpin the anti‐TB drug development process. It can mimic in vivo pharmacokinetic (PK)–pharmacodynamic (PD) attributes of selected antimicrobials, which could feed into in silico models to inform the design of clinical trials ...
Diana A. Aguilar‐Ayala, Fernando Sanz‐García, Marie Sylvianne Rabodoarivelo, Budi O. Susanto, Rebeca Bailo, Maxime R. Eveque‐Mourroux, Nicolas Willand, Ulrika S. H. Simonsson, Santiago Ramón‐García, Ainhoa Lucía, on behalf of the ERA4TB consortium   +10 more
wiley   +1 more source

Diet quality and blood pressure among pregnant women with overweight or obesity: A secondary analysis of two randomized controlled trials

Acta Obstetricia et Gynecologica Scandinavica, Volume 103, Issue 6, Page 1073-1082, June 2024.
Among women with overweight and obesity, diet quality as quantified by AHEI‐P score had no association with blood pressure in either the first or early third trimesters. Abstract Introduction Maternal obesity is a significant risk factor for hypertensive disorders of pregnancy.
Sorcha Lynch, Sarah Louise Killeen, Eileen O'Brien, Kate Mullane, Emma Hokey, Grace Mealy, Fionnuala M. McAuliffe   +6 more
wiley   +1 more source

Globalny kryzys finansowy, konsekwencje zdrowotne i wskazania dla pracowników ochrony zdrowia: przegląd literatury

Pielęgniarstwo Neurologiczne i Neurochirurgiczne, 2012
Cel. Ukazanie wpływu światowego kryzysu finansowego na zdrowie, systemy zdrowotne oraz pracowników ochrony zdrowia. Materiał i metody. Dokonano przeglądu literatury w bazach MedLine/Cinahl i Scopus, na podstawie następujących słów kluczowych i terminów ...
Venetia Notara, Alvisa Palese, Konstantinos Koulouridis, Aristidis Violatzis, Elissabet Vagka Vagka   +4 more
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Zdrowie prokreacyjne jako zasadniczy kierunek troski o zdrowie rodziny.

Fides et Ratio, 2017
Procreation health should be distinguished from reproduction health. The main targets of these two options are directed in opposition, one means care about human fecundity and overall health status second means fertility control and prochoice attitudes.
Ewa Ślizień-Kuczapska, Dorota Sys, Barbara Baranowska, Krzysztof Czajkowski   +3 more
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