Neuroprotective effects of traditional Chinese medicine using zebrafish models - a review. [PDF]
Shao J, An Y, Ding R, Wang S, Wang X.
europepmc +1 more source
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin +5 more
wiley +1 more source
Comparative analysis of zebrafish, organoid, and organ-on-chip models in breast cancer research. [PDF]
Alzaharani R, Alghadmi MA, Amiri M.
europepmc +1 more source
Abstract Background The promoters and enhancers of heat shock genes, such as the 1.5‐kb promoter of the zebrafish hsp70l gene, are valuable tools for temporal activation of transgenes. It has been widely purported that heat shock treatments result in ubiquitous expression of hsp70l‐driven transgenes.
Jong‐Su Park, Xiangyun Wei
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Zebrafish dspb-/- mutant as a model for non-dilated left ventricular cardiomyopathy: exploring cardiac dysfunction and exercise modulation. [PDF]
Munteanu S +10 more
europepmc +1 more source
Role of SoxE transcription factors in development and disease
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley +1 more source
Immunomodulatory Effects of Wheat Peptides and a Novel Octapeptide (GFNDLGKR) in Immunosuppressed Zebrafish and Mouse Models. [PDF]
Shen F +10 more
europepmc +1 more source
Secretopathies emerge as a new class of neurocristopathies
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira +3 more
wiley +1 more source
Virtual Screening and Zebrafish Phenotype-Based Evaluation Argues Against Repurposing 4-Phenylbutyrate for STXBP1-Related Disorders. [PDF]
Frick A, Whyte-Fagundes P, Baraban SC.
europepmc +1 more source
Zebrafish inversin mutants develop scoliosis in the absence of laterality defects
Abstract Background Human mutations in INVERSIN are associated with nephronophthisis, variable penetrance of situs inversus and congenital heart disease. Inversin has been shown to localize to cilia and many of the patient phenotypes are attributed to disrupted cilia function.
Christopher J. Derrick +3 more
wiley +1 more source

