Results 201 to 210 of about 419,255 (408)
Axonal outgrowth within the abnormal scaffold of brain tracts in a zebrafish mutant [PDF]
, 1994 Chetan K. Patel +2 more
openalex +1 more source
Annals of Neurology, EarlyView.Objective Gain‐of‐function (GoF) variants in KCNT1 encoding for potassium channels are associated with different epilepsy phenotypes, including epilepsy of infancy with migrating focal seizures (EIMFS), other early infantile developmental and epileptic encephalopathies, and focal epilepsy.
Marina Trivisano +13 more
wiley +1 more source
Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies
Annals of Neurology, EarlyView.Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel +10 more
wiley +1 more source
Deep learning enables automated assessments of inflammatory response in zebrafish exposed to different pollutants [PDF]
arXivIn the field of environmental toxicology, rapid and precise assessment of the inflammatory response to pollutants in biological models is critical. This study leverages the power of deep learning to enable automated assessments of zebrafish, a model organism widely used for its translational relevance to human disease pathways. We present an innovative
arxiv
Dominating Lengthscales of Zebrafish Collective Behaviour [PDF]
Collective behaviour in living systems is observed across many scales, from bacteria to insects, to fish shoals. Zebrafish have emerged as a model system amenable to laboratory study. Here we report a three-dimensional study of the collective dynamics of fifty zebrafish. We observed the emergence of collective behaviour changing between \yy{ordered} to
arxiv +1 more source
Expression of zebrafish bHLH genesngn1andnrd defines distinct stages of neural differentiation [PDF]
, 1998 Vladimir Korzh +4 more
openalex +1 more source
Advanced NanoBiomed Research, EarlyView.Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska +2 more
wiley +1 more source
An improved, high yield method for isolating nuclei from individual zebrafish embryos for single-nucleus RNA sequencing [PDF]
arXivZebrafish are an ideal system to study the effect(s) of chemical, genetic, and environmental perturbations on development due to their high fecundity and fast growth. Recently, single cell sequencing has emerged as a powerful tool to measure the effect of these perturbations at a whole embryo scale.
arxiv
Stages of embryonic development of the zebrafish
Developmental Dynamics, 1995 C. Kimmel +4 more
semanticscholar +1 more source
Advanced NanoBiomed Research, EarlyView.Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo +2 more
wiley +1 more source