Developmental Dynamics, EarlyView.Abstract Background Gene transcription is crucial for embryo and postnatal development and is regulated by the Mediator complex. Mediator is comprised of four submodules, including the kinase submodule (CKM). The CKM consists of MED13, MED12, CDK8, and CCNC.
Anna K. Leinheiser +5 more
wiley +1 more source
In Vivo Prostate Cancer Modelling: From the Pre-Clinical to the Clinical Setting. [PDF]
Life (Basel)Nascimento-Gonçalves E +3 more
europepmc +1 more source
Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain
Gareth T. Powell +19 more
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Developmental Dynamics, EarlyView.Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley +1 more source
Characterization and Phenotypic Assessment of Zebrafish Disease Models for Splice Modulation Studies. [PDF]
Methods Mol BiolThomas HR +3 more
europepmc +1 more source
The role of Rho GTPases in facial morphogenesis
Developmental Dynamics, EarlyView.The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley +1 more source
Role of Macrophages in Cardiac Remodeling: Cues From Zebrafish Heart. [PDF]
Immun Inflamm DisGaur H, Hasan M, Yalcin HC.
europepmc +1 more source
Zebrafish: A See-Through Host and a Fluorescent Toolbox to Probe Host–Pathogen Interaction
, 2012 David M. Tobin +2 more
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Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle
Developmental Dynamics, EarlyView.Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell +3 more
wiley +1 more source
Comparative Analysis of T-Cell Signatures and Astroglial Reactivity in Parkinson's Pathology Across Animal Models with Distinct Regenerative Capacities. [PDF]
Int J Mol SciIntonti S +5 more
europepmc +1 more source