Results 231 to 240 of about 209,207 (313)

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

BullFish: Software for an automated stepwise analysis of positional and postural kinematics of zebrafish locomotion. [PDF]

iScience
Sin-Hang Yeung S, Cheng HM, Lee CK, Chan WH, Luo YQ, Tin-Chun Wong G, Chuen-Chung Chang R.   +6 more
europepmc   +1 more source

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

Epilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus, Cesar Santana‐Gomez, Ruby G. Escalante, Dominique Duncan, Pedro F. Viana, Giulia Sofia Cereda, Naoto Kuroda, Aristea S. Galanopoulou   +7 more
wiley   +1 more source

Optimization of bacterial colonization in the gut of axenic and conventional zebrafish larvae using live food. [PDF]

Microbiol Spectr
Byatt G, Goffard C, Cornuault JK, Lemieux M, De Koninck P, Paquet M-E, Moineau S.   +6 more
europepmc   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

ICP1 bacteriophage treatment antagonizes colonization of the zebrafish larval intestine by <i>Vibrio cholerae</i>. [PDF]

Microbiol Spectr
Sidi Mabrouk A, Depelteau JS, Foini C, Kempff A, Jonker S, Brenzinger S, Limpens R, Majrouh M, Meijer AH, Briegel A.   +9 more
europepmc   +1 more source

From Cell Line to Fillet: A Review of Biological and Engineering Strategies in Cultivated Seafood

Food Bioengineering, EarlyView.
Bottlenecks of the cultivated seafood industry are shown, and they prevent efficiency of key production stages. These include limited cell line availability, sustainable and cost‐effective media, adaption to suspension culture, sustainable cost‐effective and edible scaffolds, food regulatory approval and acceptance of genetic modified organisms (GMO ...
Angela Trace, Miriam Wankell, Craig McFarlane, Lionel Hebbard   +3 more
wiley   +1 more source

The Protective Effect of Camellia Bee Pollen on Alcoholic Fatty Liver in Zebrafish. [PDF]

Nutrients
Luo X, Chen S, Huang A, Zhang J, Tian S, Cai C, Zhu R, Rao G.   +7 more
europepmc   +1 more source

Nutritional, phytochemical, and potential health benefits of Monostroma spp.: A systematic review

Food Biomacromolecules, EarlyView.
Abstract Monostroma spp., belonging to the green seaweed, has been known to be health‐promoting food items as prophylactic agents worldwide. It has shown wide arrays of bioactivities for the prevention and treatment of various diseases. A total of 47 articles were selected to review following the Preferred Reporting Items for Systematic reviews and ...
Md Shariful Islam
wiley   +1 more source

Aloe vera in Food Preservation: Harnessing Bioactive Constituents for Clean‐Label Innovation and Safety Assurance

Food Safety and Health, EarlyView.
Aloe vera‐derived biopolymers and nanoformulations enhance antimicrobial, antioxidant, and barrier functions in clean‐label edible coatings and films, whereas safety‐critical anthraquinone thresholds and regulatory constraints shape their translational potential.
Acharya Balkrishna, Hemant Sharma, Sonam Verma, Amar Jeet, Sumit Kumar Singh, Sharad Kumar Tripathi, Vedpriya Arya   +6 more
wiley   +1 more source