The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu +11 more
wiley +1 more source
Atrazine alters kisspeptin signaling and downstream neuroendocrine regulation following embryonic exposure in zebrafish. [PDF]
Stradtman SC +5 more
europepmc +1 more source
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
Fluopyram Induces Multilevel Toxicity in Zebrafish: Insights from Developmental Impairment, Oxidative Stress, and Metabolic Disruption. [PDF]
Wang N, Zhong Y.
europepmc +1 more source
Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer +4 more
wiley +1 more source
Early-Life Exposure to the Cooking Oil Fume Component <i>trans</i>,<i>trans</i>-2,4-Decadienal Impairs Ocular Development and Angiogenesis in Zebrafish (<i>Danio rerio</i>) Larvae. [PDF]
Wu X, Zhang X, Ruan Z.
europepmc +1 more source
β-Sitosterol β-D-glucoside (BSSG) triggers intestinal inflammation in zebrafish and mouse models prior to neurodegeneration onset. [PDF]
Terrin F +16 more
europepmc +1 more source
Loss of U11/U12 spliceosome gene <i>ZCRB1</i> leads to aberrant ciliogenesis and WNT signaling. [PDF]
Pirzada MUR +8 more
europepmc +1 more source
Employing zebrafish to understand genetic drivers of epilepsy-related comorbid behaviors. [PDF]
Ononuju C +4 more
europepmc +1 more source
Functional and Genetic Analyses Unveil the Implication of <i>hoxa4a</i> in Zebrafish Craniofacial Development. [PDF]
Sun L +5 more
europepmc +1 more source

