Insights Into the Peroxisomal Protein Inventory of Zebrafish [PDF]
Frontiers in Physiology, 2022 Peroxisomes are ubiquitous, oxidative subcellular organelles with important functions in cellular lipid metabolism and redox homeostasis. Loss of peroxisomal functions causes severe disorders with developmental and neurological abnormalities.
Maki Kamoshita +8 more
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Hnrnpa1 is essential for early zebrafish development and lipid metabolism: insights from a novel zebrafish knockout model [PDF]
Frontiers in Cell and Developmental BiologyRNA binding proteins have multiple diverse cellular functions and are often mis-regulated in disease. Despite their many cellular functions and implications in disease, very little is known about their physiological functions.
Lara U. Jansen +15 more
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Proteome Profile of Myelin in the Zebrafish Brain
Frontiers in Cell and Developmental Biology, 2021 The velocity of nerve conduction along vertebrate axons depends on their ensheathment with myelin. Myelin membranes comprise specialized proteins well characterized in mice.
Sophie B. Siems +8 more
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Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in Zebrafish. [PDF]
PLoS ONE, 2015 Carbonic anhydrase related proteins (CARPs) X and XI are highly conserved across species and are predominantly expressed in neural tissues. The biological role of these proteins is still an enigma.
Ashok Aspatwar +11 more
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Zebrafish mbnl mutants model physical and molecular phenotypes of myotonic dystrophy
Disease Models & Mechanisms, 2021 The muscleblind RNA-binding proteins (MBNL1, MBNL2 and MBNL3) are highly conserved across vertebrates and are important regulators of RNA alternative splicing.
Melissa N. Hinman +7 more
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Proteome mapping of adult zebrafish marrow neutrophils reveals partial cross species conservation to human peripheral neutrophils. [PDF]
PLoS ONE, 2013 Neutrophil granulocytes are pivotal cells within the first line of host defense of the innate immune system. In this study, we have used a gel-based LC-MS/MS approach to explore the proteome of primary marrow neutrophils from adult zebrafish.
Sachin Kumar Singh +4 more
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Current Issues in Molecular Biology, 2023 TNFAIP1 regulates cellular biological functions, including DNA replication, DNA repair, and cell cycle, by binding to target proteins. Identification of Tnfaip1-interacting proteins contributes to the understanding of the molecular regulatory mechanisms ...
Shulan Huang +8 more
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Genome Biology, 2019 Trim-Away is a recent technique to rapidly deplete a protein from any cell type. Guided by antibodies, TRIM21 selects proteins for destruction. However, the applicability of this method in model organisms has not been investigated.
Xiao Chen +7 more
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Authentication of a novel antibody to zebrafish collagen type XI alpha 1 chain (Col11a1a)
BMC Research Notes, 2021 Objective Extracellular matrix proteins play important roles in embryonic development and antibodies that specifically detect these proteins are essential to understanding their function. The zebrafish embryo is a popular model for vertebrate development
Jonathon C. Reeck +4 more
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zGrad is a nanobody-based degron system that inactivates proteins in zebrafish
eLife, 2019 The analysis of protein function is essential to modern biology. While protein function has mostly been studied through gene or RNA interference, more recent approaches to degrade proteins directly have been developed.
Naoya Yamaguchi +2 more
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