Results 21 to 30 of about 101,248 (263)
On the tubulin polymerization promoting proteins of zebrafish [PDF]
Recently, Aoki et al. [15] have been published a paper (Biochem. Biophys. Res. Commun. 445 (2014) 357-362.) in which they identified possible downstream genes required for the extension of peripheral axons in primary sensory neurons of zebrafish. Tppp was claimed as one of them but, as I show, it is the tppp3-like gene, a paralog of tppp, which plays ...
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The best-known attribute of the prion protein (PrP) is its tendency to misfold into a rogue isoform. Much less understood is how this misfolded isoform causes deadly brain illnesses. Neurodegeneration in prion disease is often seen as a consequence of abnormal PrP function yet, amazingly little is known about the normal, physiological role of PrP.
Málaga-Trillo, Edward, Sempou, Aimilia
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Neuronal cell culture from transgenic zebrafish models of neurodegenerative disease
We describe a protocol for culturing neurons from transgenic zebrafish embryos to investigate the subcellular distribution and protein aggregation status of neurodegenerative disease-causing proteins.
Jamie R. Acosta +11 more
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Zebavidin - An Avidin-Like Protein from Zebrafish
The avidin protein family members are well known for their high affinity towards D-biotin and high structural stability. These properties make avidins valuable tools for a wide range of biotechnology applications. We have identified a new member of the avidin family in the zebrafish (Danio rerio) genome, hereafter called zebavidin.
Taskinen, Barbara +15 more
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The in vitro motility assay (IVMA) is a technique that enables the measurement of the interaction between actin and myosin providing a relatively simple model to understand the mechanical muscle function. For actin-myosin IVMA, myosin is immobilized in a
Lisa-Mareike Scheid +4 more
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Proximity Dependent Biotin Labelling in Zebrafish for Proteome and Interactome Profiling
Identification of protein interaction networks is key for understanding intricate biological processes, but mapping such networks is challenging with conventional biochemical methods, especially for weak or transient interactions.
Zherui Xiong +4 more
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Macrophage‐stimulating protein and calcium homeostasis in zebrafish
To systematically identify novel gene functions essential for osteogenesis and skeletal mineralization, we performed a forward genetic mutagenesis screen in zebrafish and isolated a mutant that showed delayed skeletal mineralization. Analysis of the mutant phenotype in an osterix :nuclear‐GFP
Huitema, L.F.A. +6 more
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Retinal degeneration in rpgra mutant zebrafish
Introduction: Pathogenic mutations in RPGRORF15, one of two major human RPGR isoforms, were responsible for most X-linked retinitis pigmentosa cases. Previous studies have shown that RPGR plays a critical role in ciliary protein transport.
Xiliang Liu +16 more
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Characterization of the RNA-binding protein Musashi1 in zebrafish
Musashi (Msi) is an evolutionarily conserved gene family of RNA-binding proteins (RBPs) that is preferentially expressed in the nervous system. The first member of the Msi family was identified in Drosophila. Drosophila Msi plays an important role in regulating asymmetric cell division of the sensory organ precursor cells.
Shibata, Shinsuke +5 more
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Hepatic proteome network data in zebrafish (Danio rerio) liver following dieldrin exposure
Dieldrin is an environmental contaminant that adversely affects aquatic organisms. The data presented in this study are proteomic data collected in liver of zebrafish that were exposed to the pesticide in a dietary exposure.
Denina B.D. Simmons +4 more
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