Results 31 to 40 of about 101,248 (263)
Profiling subcellular localization of nuclear-encoded mitochondrial gene products in zebrafish
Life Science Alliance, 2023 The vast majority (99%) of mitochondrial proteins are encoded by the nuclear genome, synthesized in the cytosol and imported into the organelle. Here we study the principles of mitochondrial import in vivo from the RNA perspective using zebrafish.
Barbara Uszczynska-Ratajczak +7 more
doaj +1 more source
Bone morphogenetic proteins in the early development of zebrafish [PDF]
The FEBS Journal, 2007 Bone morphogenetic proteins (BMPs) are known to be widely involved in various biological processes. Many of the members of the BMP family, as well as related factors, receptors and molecules in the BMP signaling pathway, have been isolated, but their precise functions are still unclear.
openaire +2 more sources
Crk adaptor proteins are necessary for the development of the zebrafish retina
Developmental Dynamics, 2021 AbstractBackgroundThe development of the central nervous system (CNS) requires critical cell signaling molecules to coordinate cell proliferation and migration in order to structure the adult tissue. Chicken tumor virus #10 Regulator of Kinase (CRK) and CRK‐like (CRKL) are adaptor proteins with pre‐metazoan ancestry and are known to be required for ...
Helaina R. Stergas +5 more
openaire +3 more sources
Data in Brief, 2017 Quantitative proteins analysis was carried out in the hypothalamus of zebrafish following dietary exposure to the legacy pesticide dieldrin. Data were collected using iTRAQ labeling methodology and data were acquired using a hybrid quadrupole Orbitrap (Q
Andrew M. Cowie +5 more
doaj +1 more source
Agouti-Signalling Protein Overexpression Reduces Aggressiveness in Zebrafish
Biology, 2023 Feeding motivation plays a crucial role in food intake and growth. It closely depends on hunger and satiation, which are controlled by the melanocortin system. Overexpression of the inverse agonist agouti-signalling protein (ASIP) and agouti-related protein (AGRP) leads to enhanced food intake, linear growth, and weight. In zebrafish, overexpression of
Ana Rocha +3 more
openaire +4 more sources
Evolution and Expression of Paxillin Genes in Teleost Fish. [PDF]
PLoS ONE, 2016 BACKGROUND:Paxillin family proteins regulate intracellular signaling downstream of extracellular matrix adhesion. Tissue expression patterns and cellular functions of Paxillin proteins during embryo development remain poorly understood. Additionally, the
Andrew E Jacob +2 more
doaj +1 more source
Promoter Binding and Nuclear Retention Features of Zebrafish IRF Family Members in IFN Response
Frontiers in Immunology, 2022 Interferon regulatory factors (IRFs) constitute a family of transcription factors that synchronize interferon (IFN) antiviral response through translocating to nucleus and binding to the promoters of IFN and IFN-stimulated genes (ISGs).
Li-Li An +20 more
doaj +1 more source
Zebrafish do not have a calprotectin ortholog.
PLoS ONEThe protein heterodimer calprotectin and its component proteins, S100A8 and S100A9, play important antibacterial and pro-inflammatory roles in the mammalian innate immune response.
Kona N Orlandi, Michael J Harms
doaj +1 more source
Genetic zebrafish models of neurodegenerative diseases
Neurobiology of Disease, 2010 As a consequence of the widespread use of zebrafish in developmental biology studies, an extensive array of experimental tools and techniques has been assembled; it has recently become apparent that these might be exploited in the analysis of human ...
Oliver Bandmann, Edward A. Burton
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source