Results 41 to 50 of about 107,862 (214)

Promoter Binding and Nuclear Retention Features of Zebrafish IRF Family Members in IFN Response

Frontiers in Immunology, 2022
Interferon regulatory factors (IRFs) constitute a family of transcription factors that synchronize interferon (IFN) antiviral response through translocating to nucleus and binding to the promoters of IFN and IFN-stimulated genes (ISGs).
Li-Li An, Li-Li An, Xiang Zhao, Xiang Zhao, Xiu-Ying Gong, Xiu-Ying Gong, Yi-Lin Li, Yi-Lin Li, Zi-Ling Qu, Zi-Ling Qu, Hao-Yu Sun, Hao-Yu Sun, Wen-Hao Guo, Cheng Dan, Jian-Fang Gui, Jian-Fang Gui, Jian-Fang Gui, Yi-Bing Zhang, Yi-Bing Zhang, Yi-Bing Zhang, Yi-Bing Zhang   +20 more
doaj   +1 more source

Mutations in ap1b1 Cause Mistargeting of the Na(+)/K(+)-ATPase Pump in Sensory Hair Cells. [PDF]

, 2013
The hair cells of the inner ear are polarized epithelial cells with a specialized structure at the apical surface, the mechanosensitive hair bundle.
Kindt, Katie, Nicolson, T., Kindt, K., Katie Kindt, Teresa Nicolson, Schmid, Bettina, Bettina Schmid, Grisham, R., Finger-Baier, Karin, Clemens Grisham, Rachel, Rachel Clemens Grisham, Nicolson, Teresa, Schmid, B., Karin Finger-Baier, Finger-Baier, K.   +14 more
core   +1 more source

Zebrafish do not have a calprotectin ortholog.

PLoS ONE
The protein heterodimer calprotectin and its component proteins, S100A8 and S100A9, play important antibacterial and pro-inflammatory roles in the mammalian innate immune response.
Kona N Orlandi, Michael J Harms
doaj   +1 more source

A phenotypic screen in zebrafish identifies a novel small-molecule inducer of ectopic tail formation suggestive of alterations in non-canonical Wnt/PCP signaling

, 2013
Zebrafish have recently emerged as an attractive model for the in vivo bioassay-guided isolation and characterization of pharmacologically active small molecules of natural origin.
Alexander D. Crawford, Crawford, Alexander D, Alexander I. Gray, Cordero-Maldonado, María Lorena, de Witte, Peter A M, Gray, Alexander I, Alan L Harvey, Camila V. Esguerra, Gebruers, Evelien, Evelien Gebruers, Harvey, Alan L, Carol Clements, Clements, Carol, Alexander D Crawford, Edrada-Ebel, Ruangelie, Camila V Esguerra, Alan L. Harvey, Ruangelie Edrada-Ebel, Esguerra, Camila V, María Lorena Cordero-Maldonado, Alexander I Gray, Peter A M de Witte, Cordero Maldonado, María Lorena, Peter A. M. de Witte   +23 more
core   +1 more source

Dynamic cell rearrangements shape the cranial vascular network of developing Zebrafish embryos [PDF]

, 2013
To form the complex network of endothelial tubes making up the vasculature, a number of vessels have to interact and connect to each other during development.
Lenard, Anna
core   +1 more source

Epigenetic regulation in zebrafish development: the roles of polycomb group proteins in heart and pectoral fin development

Epigenetics Communications
Background Polycomb group proteins, known for their role in epigenetic gene silencing, are critical regulators of cell fate and tissue development across species.
Pratiksha S. Kavade, Saili S. Parab, Vincenza Capone, Daniela Carannante, Concetta Ambrosino, Lucia Altucci, Vincenzo Carafa   +6 more
doaj   +1 more source

trappc11is required for protein glycosylation in zebrafish and humans

Molecular Biology of the Cell, 2016
Activation of the unfolded protein response (UPR) can be either adaptive or pathological. We term the pathological UPR that causes fatty liver disease a “stressed UPR.” Here we investigate the mechanism of stressed UPR activation in zebrafish bearing a mutation in the trappc11 gene, which encodes a component of the transport protein particle (TRAPP ...
DeRossi, Charles, Vacaru, Ana, Rafiq, Ruhina, Cinaroglu, Ayca, Imrie, Dru, Nayar, Shikha, Baryshnikova, Anastasia, Milev, Miroslav P., Stanga, Daniela, Kadakia, Dhara, Gao, Ningguo, Chu, Jaime, Freeze, Hudson H., Lehrman, Mark A., Sacher, Michael, Sadler, Kirsten C.   +15 more
openaire   +2 more sources

Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish

Communications Biology, 2022
The role of sperm membrane proteins DCST1 and DCST2 in gamete fusion is extended to zebrafish in showing that these interdependent proteins are required for sperm-egg binding.
Taichi Noda, Andreas Blaha, Yoshitaka Fujihara, Krista R. Gert, Chihiro Emori, Victoria E. Deneke, Seiya Oura, Karin Panser, Yonggang Lu, Sara Berent, Mayo Kodani, Luis Enrique Cabrera-Quio, Andrea Pauli, Masahito Ikawa   +13 more
doaj   +1 more source

A ligand-receptor interactome atlas of the zebrafish

iScience, 2023
Summary: Studies in zebrafish can unravel the functions of cellular communication and thus identify novel bench-to-bedside drugs targeting cellular communication signaling molecules.
Milosz Chodkowski, Andrzej Zielezinski, Savani Anbalagan   +2 more
doaj   +1 more source

Meis family proteins are required for hindbrain development in the zebrafish [PDF]

Development, 2002
Meis homeodomain proteins function as Hox-cofactors by binding Pbx and Hox proteins to form multimeric complexes that control transcription of genes involved in development and differentiation. It is not known what role Meis proteins play in these complexes, nor is it clear which Hox functions require Meis proteins in vivo. We now show that a divergent
Seong-Kyu, Choe, Vlachakis, Nikolaos, Sagerstrom, Charles G.   +2 more
openaire   +3 more sources