Results 291 to 300 of about 373,753 (331)

Parkinson's‐Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa

Movement Disorders, EarlyView.
Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark, Hannah A. Staley, Ann M. Titus, Julian Agin‐Liebes, Alicia Garrido, Laura Hughes, Nicolas Dzamko, Rebecca L. Wallings, Malú Gámez Tansey   +8 more
wiley   +1 more source

Evaluating variants of uncertain significance in adult zebrafish via prime editing: a proof of concept with a COL1A2 variant. [PDF]

BMC Med Genomics
Vanhooydonck M, Debaenst S, Vanbelleghem E, De Saffel H, Syx D, Sips P, Coucke PJ, Willaert A, Callewaert B.   +8 more
europepmc   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

Medicinal Research Reviews, EarlyView.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara, Gómez‐Santacana Xavier, Llebaria Amadeu, Rovira Xavier   +3 more
wiley   +1 more source

Evaluation of natural products bioactivity in cardiovascular diseases utilizing zebrafish models: a comprehensive review. [PDF]

Front Pharmacol
Wang Y, Meng X, Song X, Wang L, Meng X, Du X, Yusupov Z, Tojibaev K, Wang Y, He M, Sun M.   +10 more
europepmc   +1 more source

Dual role of ACE2 in regulating inflammation triggered by Omicron S1 and other SARS-CoV-2 Spike variants. [PDF]

Front Immunol
Pedoto A, Lozano-Gil JM, Ocaña-Esparza M, Conesa-Hernández AM, Candel S, Cayuela ML, Mulero V, Tyrkalska SD.   +7 more
europepmc   +1 more source

Effect of Centella asiatica ethanol extract on zebrafish larvae (Danio rerio) insomnia model through inhibition of Orexin, ERK, Akt and p38

Zamroni Afif, Mochammad Istiadjid Eddy Santoso, Nurdiana Nurdiana, Husnul Khotimah, Irawan Satriotomo, Shahdevi Nandar Kurniawan, Hidayat Sujuti, Dheka Sapti Iskandar, Annisatul Hakimah   +8 more
openalex   +1 more source

Effects and Mechanisms of Dufulin Toxicity on Zebrafish, <i>Danio rerio</i>. [PDF]

Toxics
Jia S, Li M, Yuan G, Wang L, Chi H.
europepmc   +1 more source

Temperature-dependence of early development of zebrafish and the consequences for laboratory use and animal welfare. [PDF]

PLoS One
Miller A, Schröder KL, Braun KE, Steindorf C, Ottermanns R, Roß-Nickoll M, Hollert H, Backhaus T.   +7 more
europepmc   +1 more source