Results 31 to 40 of about 117,302 (307)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An Interleaved Zero-Voltage Zero-Current Switching High Step-Up DC-DC Converter

IEEE Access, 2021
An interleaved zero-voltage zero-current switching (ZVZCS) high step-up DC-DC converter is proposed for modern photovoltaic power generation systems. The proposed converter can achieve high voltage conversion gain without operating under extreme duty ...
Binxin Zhu, Shihuan Chen, Yao Zhang, Yu Huang   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A Hybrid Resonant ZVZCS Three-Level Converter Suitable for Photovoltaic Power DC Distribution System

IEEE Access, 2020
A novel hybrid resonant zero-current- switching (ZCS) three-level DC-DC converter based on a dual transformer with two output filter capacitors is proposed in this paper, which is suitable for application in distributed photovoltaic power generation at ...
Syed Waqar Azeem, Wu Chen, Irfan Tariq, Haihan Ye, David Kaija   +4 more
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Zczvt Inverters With Magnetically Coupled Auxiliary Pole

Eletrônica de Potência, 2010
Existing Zero-Current Transition and Zero- Current Zero-Voltage Transition inverters provides favorable switching conditions for IGBT semiconductors increasing significantly the reactive energy of the converter.
Mário Lúcio da Silva Martins, Carlos Marcelo de Oliveira Stein, Jumar Luís Russi, José Renes Pinheiro, Hélio Leães Hey   +4 more
doaj   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

Arthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart, Anne Horne, Angelo Gaffo, Lisa K. Stamp, N. Lawrence Edwards, Nicola Dalbeth   +5 more
wiley   +1 more source

Soft-switching single inductor current-fed push-pull converter for PV applications

, 2014
A switching control strategy is proposed for single inductor current-fed push-pull converter with a secondary side active voltage doubler rectifier or a voltage rectifier used in photovoltaic (PV) grid interfacing. The proposed switching control strategy
Vilathgamuwa, D. Mahinda, Nayanasiri, D.R., D. R. Nayanasiri, Maskell, D.L., Beng, Gilbert Foo Hock, Gilbert Foo Hock Beng, D. L. Maskell, D. M. Vilathgamuwa   +7 more
core   +1 more source

Analysis and Implementation of an Interleaved High Step‐Up Converter With Zero‐Voltage‐Switching

IET Power Electronics
In this paper, a high step‐up DC‐DC converter is presented. The input current ripple is reduced by adding the interleaving technique on the input side.
Marzieh Mohammadi Jouzdani, Omid Haghparast Naeini, Mahdi Shaneh, Tohid Nouri   +3 more
doaj   +1 more source