Results 41 to 50 of about 8,288,511 (300)

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

Soft-switching single inductor current-fed push-pull converter for PV applications

, 2014
A switching control strategy is proposed for single inductor current-fed push-pull converter with a secondary side active voltage doubler rectifier or a voltage rectifier used in photovoltaic (PV) grid interfacing. The proposed switching control strategy
Vilathgamuwa, D. Mahinda, Nayanasiri, D.R., D. R. Nayanasiri, Maskell, D.L., Beng, Gilbert Foo Hock, Gilbert Foo Hock Beng, D. L. Maskell, D. M. Vilathgamuwa   +7 more
core   +1 more source

Disease Course After Anti‐CD20 Discontinuation in Secondary Progressive Multiple Sclerosis—A Multicenter Long‐Term Longitudinal Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe long‐term outcomes after anti‐CD20 discontinuation in selected patients with secondary progressive multiple sclerosis (SPMS) who remained without subsequent disease‐modifying therapy (DMT). Methods We retrospectively analyzed data from four centers in Austria and Switzerland.
Ferdinand Otto, Dariia Kliushnikova, Richard Friedrich Radlberger, Sinan Yasaroglu, Tobias Moser, Andrea Harrer, Kitty Kratzer, Wolfgang Hitzl, Christiane Gradl, Martin Schmidauer, Patrick Roth, Harald Hegen, Peter Wipfler   +12 more
wiley   +1 more source

Steady-state analysis of full-bridge zero-current switching converter

, 2000
A steady-state analysis of the full-bridge zero-current-switched (FB-ZCS) pulsewidth modulation (PWM) converter is presented. The FB-ZCS is fully able to incorporate parasitic parameters, and zero-current turn-off characteristics.
Luo, S., Iannello, C., Batarseh, I.
core   +2 more sources

A Novel Three-Phase Six-Switch PFC Rectifier with Zero-Voltage-Switching and Zero-Current-Switching Features

Energies, 2019
A novel three-phase power-factor-correction (PFC) rectifier with zero-voltage-switching (ZVS) in six main switches and zero-current-switching (ZCS) in the auxiliary switch is proposed, analyzed, and experimentally verified.
Chun-Wei Lin, Chang-Yi Peng, Huang-Jen Chiu   +2 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Power conversion using zero current soft switching

, 1992
A zero current soft switching power converter (10) is provided in which a link capacitor (20) is coupled between a source switch S1 and a source switch S2.
Ehsani, Mehrdad
core   +1 more source

An Interleaved Step-up DC-DC Converter with Lossless Snubber

Majlesi Journal of Electrical Engineering
In this paper, an interleaved step-up converter with two lossless snubbers is introduced, where the snubbers ensure zero-current switching for the main switches, eliminating the need for extra switches.
Arman Hovsep, Majid Delshad, Bahador Fani, Mahdi Sajadieh   +3 more
doaj   +1 more source

Operation Analysis of Soft Switching PWM DC-DC Converter with Secondary Snubber

Communications, 2013
The paper deals with analysis of operation of a soft switching PWM DC-DC full-bridge converter with new energy recovery turn-off snubber on secondary side of high frequency power transformer.Principal equations are derived for individual operation states.
Jaroslav Dudrik, Marcel Bodor, Daniel Trip Nistor   +2 more
doaj   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source