How phagocytic cells kill bacteria: Lessons from a professional killer
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Evaluation Of The Zero Sequence Impedance Of Overhead High Voltage Lines
As known, the guard wires of overhead high voltage are usually grounded through the grounding systems of support and of the terminal stations. They do affect the zero sequence impedance value of the line, Z0, which is generally, calculated assuming that the wires guard are at ground potential.
openaire +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Design of a new type of integrated test bench for mine-used high-voltage protector
A new type of integrated test bench for mine-used high-voltage protector was designed. The overall structure and design schemes of software and hardware of the test bench were introduced.
HUANG Hesong +3 more
doaj +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Circulating Current Suppression and Midpoint Potential Balance of Flexible DC T-Type Three-Level Bidirectional Converter for Urban Rail Transit [PDF]
[Objective] A bidirectional converter integrates traction, feedback, and reactive power compensation and is the primary choice for upgrading the main equipment of an urban rail DC traction power supply system.
LIU Jianhua, LI Dongdong, LI Hao
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
The paper proposed a design scheme of selective leakage protection circuit based on method of amplitude discrimination and phase discrimination for electrical control equipments of fully mechanized devices of coal mine underground.The selective leakage ...
FAN Yi-long~, LI Hang~, YOU Guo-dong~
doaj
Influence of magnetic saturation effects on the fault detection of induction motors
In this paper, the influence of impact damage to the induction motors on the zero-sequence voltage and its spectrum is presented. The signals detecting the damages result from a detailed analysis of the formula describing this voltage component which is ...
Drozdowski Piotr, Duda Arkadiusz
doaj +1 more source

