Results 41 to 50 of about 23,335 (269)

Paramagnetic Rim Lesions and Choroid Plexus Volume at Diagnosis Are Associated With Cognitive Progression Independent of Relapse and MRI Activity in Early Relapsing–Remitting Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) and choroid plexus (CP) enlargement reflect smoldering inflammation in multiple sclerosis. Their role in cognitive progression remains unexplored. Eighty‐seven early relapsing–remitting MS patients were enrolled at diagnosis and followed longitudinally.
Stefano Ziccardi, Damiano Marastoni, Agnese Tamanti, Pietro Biasi, Valentina Visani, Annalisa Colombi, Tom A. Fuchs, Monica Sicchieri, Chiara Eccher, Francesco Guarnaccia, Milena Calderone, Valentina Camera, Francesca Benedetta Pizzini, Roberta Magliozzi, Marco Castellaro, Massimiliano Calabrese   +15 more
wiley   +1 more source

Interleaved zero voltage switching forward converter with less switches

Electronics Letters, 2008
An interleaved zero voltage switching (ZVS) forward converter with less switches is presented. Two forward converters with active clamp technique are adopted in the circuit to achieve interleaved pulse-width-modulation (PWM) operation and load current sharing.
B.R. Lin, W.C. Li
openaire   +1 more source

An optimized scheme for OLTCs of distribution transformers using flywheel motors

Zhejiang dianli
In the switching process of on-load tap changers （OLTCs） for distribution transformers， electric arcs are likely to occur at the contacts， which have an adverse impact on the service life and normal operation of the equipment.
LI Jiang, GUO Surong, LIU Bo
doaj   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

Improved ASHCPWM with Reduced IGBT Switching Actions and Kalman Filter-Based Zero-Sequence Suppression for Open-End Winding PMSM Drives

Micromachines
To improve the dc-bus voltage utilization while reducing the commutation burden of an insulated gate bipolar transistor (IGBT)-based open-end winding permanent magnet synchronous motor (OEW-PMSM) drive, this paper proposes an improved alternate sub ...
Yu Zhang, Mingzhe Qu, Hongjia Xie, Yang Xia, Liangxing Hu   +4 more
doaj   +1 more source

Role of induced exchange bias in zero field spin–orbit torque magnetization switching in Pt/[Ni/Co]/PtMn

AIP Advances, 2020
Current induced magnetization switching is of particular interest to develop non-volatile magnetic memories (MRAM). We studied spin–orbit torque (SOT) switching in a Pt/ferromagnet/antiferromagnet Pt/[Co/Ni]2/PtMn Hall cross. For the as-deposited sample,
Maxime Vergès, Vinod Kumar, Po-Hung Lin, Stéphane Mangin, Chih-Huang Lai   +4 more
doaj   +1 more source

Disease Course After Anti‐CD20 Discontinuation in Secondary Progressive Multiple Sclerosis—A Multicenter Long‐Term Longitudinal Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe long‐term outcomes after anti‐CD20 discontinuation in selected patients with secondary progressive multiple sclerosis (SPMS) who remained without subsequent disease‐modifying therapy (DMT). Methods We retrospectively analyzed data from four centers in Austria and Switzerland.
Ferdinand Otto, Dariia Kliushnikova, Richard Friedrich Radlberger, Sinan Yasaroglu, Tobias Moser, Andrea Harrer, Kitty Kratzer, Wolfgang Hitzl, Christiane Gradl, Martin Schmidauer, Patrick Roth, Harald Hegen, Peter Wipfler   +12 more
wiley   +1 more source

Analysis of Intrinsic Switching Losses in Superjunction MOSFETs Under Zero Voltage Switching

Energies, 2020
Switching losses of power transistors usually are the most relevant energy losses in high-frequency power converters. Soft-switching techniques allow a reduction of these losses, but even under soft-switching conditions, these losses can be significant ...
Maria R. Rogina, Alberto Rodriguez, Diego G. Lamar, Jaume Roig, German Gomez, Piet Vanmeerbeek   +5 more
doaj   +1 more source

A phase‐shift modulated series resonant converter achieving zero‐voltage and zero‐current switching for wide output voltage range battery charging applications

IET Power Electronics, 2022
In this article, a phase‐shift modulated zero‐voltage and zero‐current switching (ZVZCS) series resonant converter (SRC) was proposed for constant current (CC) and constant voltage (CV) charging operating at the series resonant frequency.
Yanke Liang, Xu Liu, Shixuan Lyu
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source