Results 51 to 60 of about 9,977,087 (284)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Achievable Rates for Full-Duplex Massive MIMO Systems Over Rician Fading Channels

open access: yesIEEE Access, 2018
We study the uplink and downlink achievable rate of full-duplex large-scale multi-input multioutput (MIMO) systems with a base station (BS) and users over Rician fading channels, based on maximum ratio combining/maximum ratio transmission and zero ...
Juan Liu   +4 more
doaj   +1 more source

Compute-and-forward transmission scheme in cell-free massive MIMO systems

open access: yesICT Express, 2023
Cell-free massive multi-input-multi-output (MIMO) systems comprise a large number of distributed access points (APs) to serve a small number of user equipments (UEs). In this paper, compute-and-forward (CF) is investigated for uplink in cell-free massive
Hua Jiang, Linghong Kong, Sidan Du
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Failed Zero Forcing Numbers of Trees and Circulant Graphs

open access: yesTheory and Applications of Graphs
Given a graph $G$, the zero forcing number of $G$, $Z(G)$, is the smallest cardinality of any set $S$ of vertices on which repeated applications of the forcing rule (described below) results in all vertices being in $S$.
Luis Gomez   +4 more
doaj   +1 more source

The zero forcing span of a graph

open access: yes, 2023
In zero forcing, the focus is typically on finding the minimum cardinality of any zero forcing set in the graph; however, the number of cardinalities between $0$ and the number of vertices in the graph for which there are both zero forcing sets and sets ...
Jacob, Bonnie
core  

Ethical Foreground and Background in Adult Educator Work

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

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