Results 51 to 60 of about 6,063,894 (295)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

The TIPMIP Earth system model experiment protocol: phase 1 [PDF]

Geoscientific Model Development
We describe a new Earth system model (ESM) experiment protocol, as part of the international Tipping Points Modelling Intercomparison Project (TIPMIP) project. We propose this as a protocol for the Coupled Model Intercomparison Project 7 (CMIP7).
C. Jones, I. Bossert, D. P. Dennis, D. P. Dennis, H. A. Jeffery, C. D. Jones, C. D. Jones, T. Koenigk, T. Koenigk, S. Loriani, S. Loriani, B. Sanderson, R. Séférian, K. Wyser, K. Wyser, S. Yang, M. Abe, S. Bathiany, S. Bathiany, P. Braconnot, V. Brovkin, V. Brovkin, F. A. Burger, F. A. Burger, P. Cadule, F. S. Castruccio, G. Danabasoglu, A. Dittus, J. F. Donges, J. F. Donges, J. F. Donges, F. Fröb, F. Fröb, T. L. Frölicher, T. L. Frölicher, G. Georgievski, C. Guo, A. Hu, P. Lawrence, P. Lerner, P. Lerner, J. Licón-Saláiz, B. Otto-Bliesner, A. Romanou, A. Romanou, E. Shevliakova, Y. Silvy, Y. Silvy, D. Swingedouw, J. Tjiputra, J. Walton, A. Wiltshire, A. Wiltshire, R. Winkelmann, R. Winkelmann, R. Wood, T. Yokohata, T. Ziehn   +57 more
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Failed Zero Forcing Numbers of Trees and Circulant Graphs

Theory and Applications of Graphs
Given a graph $G$, the zero forcing number of $G$, $Z(G)$, is the smallest cardinality of any set $S$ of vertices on which repeated applications of the forcing rule (described below) results in all vertices being in $S$.
Luis Gomez , Karla Rubi, Jorden Terrazas , Rigoberto Florez , Darren A. Narayan   +4 more
doaj   +1 more source

The zero forcing span of a graph

, 2023
In zero forcing, the focus is typically on finding the minimum cardinality of any zero forcing set in the graph; however, the number of cardinalities between $0$ and the number of vertices in the graph for which there are both zero forcing sets and sets ...
Jacob, Bonnie
core  

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Failed Skew Zero Forcing Numbers of Path Powers and Circulant Graphs

AppliedMath
For a graph G, the zero forcing number of G, Z(G), is defined to be the minimum cardinality of a set S of vertices for which repeated applications of the forcing rule results in all vertices being in S. The forcing rule is as follows: if a vertex v is in
Aidan Johnson, Andrew Vick, Rigoberto Flórez, Darren A. Narayan   +3 more
doaj   +1 more source

Nutritional management and maize variety combination effectively control Striga asiatica in southern Africa

CABI Agriculture and Bioscience, 2022
Maize (Zea mays L.) is an important staple food crop in sub-Saharan Africa (SSA) and contributes significantly to food security. Due to Striga, maize yield loss is estimated between 20 and 80% forcing some farmers to abandon their land therefore ...
Simbarashe Mutsvanga, Edmore Gasura, Peter S. Setimela, Cacious S. Nyakurwa, Stanford Mabasa   +4 more
doaj   +1 more source

Zero forcing propagation time on oriented graphs [PDF]

, 2017
Zero forcing is an iterative coloring procedure on a graph that starts by initially coloring vertices white and blue and then repeatedly applies the following rule: if any blue vertex has a unique (out-)neighbor that is colored white, then that neighbor ...
Minerva Catral, Berliner, Adam, Hogben, Leslie, Steve Butler, Warnberg, Nathan, Butler, Steve, Catral, Minerva, Chassidy Bozeman, Leslie Hogben, Adam Berliner, Nathan Warnberg, Bozeman, Chassidy, Jephian C.-H. Lin, Michael Young, Kroschel, Brenda K, Lin, Jephian C-H, Young, Michael, Kroschel, Brenda, Lin, Jephian, Brenda Kroschel   +19 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source