Results 81 to 90 of about 52,825 (304)
Estimating the Ratio of Means in a Zero-Inflated Poisson Mixture Model
StatsThe problem of estimating the ratio of the means of a two-component Poisson mixture model is considered, when each component is subject to zero-inflation, i.e., excess zero counts. The resulting zero-inflated Poisson mixture (ZIPM) model can be viewed as
Michael Pearce, Michael D. Perlman
doaj +1 more source
Advanced Science, EarlyView.We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang +11 more
wiley +1 more source
On the role of money growth targeting under inflation targeting regime. [PDF]
The mainstream inflation-targeting literature makes the strong assumption that the central bank can exactly target the interest rate which affects investment and consumption decisions and hence the money supply plays no role in the monetary policy ...
Meixing DAI
core +2 more sources
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Advanced Science, EarlyView.Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao +7 more
wiley +1 more source
Should Central Banks Raise their Inflation Targets? Some Relevant Issues [PDF]
Should central banks, because of the zero-lower-bound problem, raise their inflation-rate targets? Several arguments are relevant. (1) In the absence of the ZLB, the optimal steady-state inflation rate, according to standard New Keynesian reasoning, lies
Bennett T. McCallum
core
Upper Bounds on the Mass of Fundamental Fields from the Primordial Universe
The Astrophysical JournalWe study the fluctuations in the vacuum zero-point energy associated with quantum fields and their statistical distributions during inflation. It is shown that the perturbations in the vacuum zero-point energy have large amplitudes that are highly non ...
Hassan Firouzjahi
doaj +1 more source
Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
Advanced Science, EarlyView.In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
Beyond inflation targeting: should central banks target the price level? [PDF]
Over the last two decades, many central banks have adopted formal inflation targets to guide the conduct of monetary policy. During this period, inflation has come down in many countries and been relatively stable by historical standards.
George A. Kahn
core
StatsDatasets with many zero outcomes are common in real-world studies and often exhibit overdispersion and strong correlations among predictors, creating challenges for standard count models.
HM Nayem, B. M. Golam Kibria
doaj +1 more source