Results 111 to 120 of about 57,513 (312)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

On the Zeros of Polynomials

open access: yesCommunications, Faculty Of Science, University of Ankara Series A1Mathematics and Statistics, 1977
1. Govil and Rahman [1, Theorem 1] have proved the fol- lowing theorem.n Theorem A. Let p (z) = £ aj^ k“0 z’^ ( 0) be a polynomiai ofdegree n with complex coefficients such that for some a>«-1 I a^ •11-2 a' I »ol-Then p (z) has ali its zeros in |z Kj, where Kj is the greatest positive root of the trinomial equation K"+ı - 2K" + 1 =
openaire   +4 more sources

Chromatic roots are dense in the whole complex plane

open access: yes, 2004
I show that the zeros of the chromatic polynomials P-G(q) for the generalized theta graphs Theta((s.p)) are taken together, dense in the whole complex plane with the possible exception of the disc \q - l\ < l.
Sokal, AD
core  

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye   +11 more
wiley   +1 more source

On Polynomials Associated with Finite Topologies

open access: yesAxioms
Let τ be a topology on the finite set Xn. We consider the open-set polynomial associated with the topology τ. Its coefficients are the cardinalities of sets Uj=Uj(τ) of open sets of size j=0,…,n.
Moussa Benoumhani, Brahim Chaourar
doaj   +1 more source

Zeros of Hurwitz zeta functions

open access: yes, 1976
All complex zeros of each Hurwitz zeta function are shown to lie in a vertical strip. Trivial real zeros analogous to those for the Riemann zeta function are found. Zeros of two particular Hurwitz zeta functions are calculated.
Robert Spira
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Improving the Asymptotic Properties of Discrete System Zeros in Fractional-Order Hold Case

open access: yesJournal of Applied Mathematics, 2013
Remarkable improvements in the asymptotic properties of discrete system zeros may be achieved by properly adjusted fractional-order hold (FROH) circuit.
Cheng Zeng, Shan Liang, Yingying Su
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

Computation of H-infinity norm of linear discrete-time periodic systems

open access: yes, 2006
We propose an efficient an numerically reliable procedure for the computation of H-infinity norm of discrete-time linear periodic systems. The new procedure is general being applicable to both standard as well as descriptor periodic systems with time ...
Varga, Andreas
core  

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