Results 101 to 110 of about 57,513 (312)
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Zeros of univariate interval polynomials
, 2007 Polynomials with perturbed coefficients, which can be regarded as interval polynomials, are very common in the area of scientific computing due to floating point operations in a computer environment.
Chen, Falai +5 more
core +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Some inequalities for rational function with prescribed poles and restricted zeros
Demonstratio MathematicaIn this article, we first prove some auxiliary results in the form of lemmas using an improved Schwarz lemma at the boundary recently proved by Mercer. Furthermore, we establish some new inequalities for rational functions on the unit disk in the complex
Soraisam Robinson +2 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
La hipòtesi de Riemann: El gran repte pendent
Mètode Science Studies Journal: Annual Review, 2018 La hipòtesi de Riemann és una afirmació, no demostrada, que fa referència als zeros de la funció zeta de Riemann. Bernhard Riemann calculà els sis primers zeros no trivials d’aquesta funció i observà que tots estaven sobre una mateixa recta.
Pilar Bayer
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Zeros of difference polynomials
, 1992 Let Δ be the difference operator defined by Δf(x) = f(x + 1) − f(x). The polynomial Δmxn of degree n − m is known to have n − m collinear zeros. We study the distribution of these zeros and relate them to zeros of Hermite polynomials.
Wavrik, John J, Evans, Ronald J
core +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source