Novel Bioresorbable Bone Wax for Potentiated Hemostasis and Osteogenesis. [PDF]
Adv Sci (Weinh)The synthesized bioresorbable bone wax material for hemostasis and osteogenesis. The preparation process of the novel resorbable bone wax and its mechanism of accelerating coagulation and promoting osteoregeneration through blood cell aggregation. Abstract Orthopedic surgery faces dual challenges of uncontrolled bleeding and poor bone regeneration at ...
Feng L +10 more
europepmc +2 more sources
SMart Nanoparticle-Hydrogel Hybrid System for Synergistic Eradication of Infection and Promotion of Wound Healing. [PDF]
Adv Sci (Weinh)The integrated system, comprising bacterial‐targeted photothermal nanoparticles (Fe2O3‐CS@RBP) and multifunctional hydrogels (PAOC‐3@BA) modules, achieves rapid wound healing within one week. This work introduces a smart therapeutic platform that integrates bacterial targeting, self‐regulating photothermal therapy, tissue adhesion, and stimulus ...
Wan H, Tan H, Zhao X.
europepmc +2 more sources
Pulmonary sarcoidosis is associated with exosomal vitamin D-binding protein and inflammatory molecules [PDF]
, 2022 BACKGROUND: Sarcoidosis is an inflammatory granulomatous disorder characterized by accumulation of TH1-type CD4+T cells and immune effector cells within affected organs, most frequently the lungs.
Ana Lukic +9 more
core +1 more source
Proteomics of rimmed vacuoles define new risk allele in inclusion body myositis [PDF]
, 2016 OBJECTIVE: Sporadic inclusion body myositis (sIBM) pathogenesis is unknown; however, rimmed vacuoles (RVs) are a constant feature. We propose to identify proteins that accumulate within RVs.
Brady, S +16 more
core +1 more source
Análise proteômica de células não fagocíticas na fase inicial da infecção por trypanosoma cruzi [PDF]
, 2015 Dissertação (mestrado)—Universidade de Brasília, Faculdade de Medicina, Programa de Pós-Graduação em Patologia Molecular, 2015.A Doença de Chagas é considerada uma doença negligenciada, endêmica na América Latina. e com tratamento ainda ineficaz.
Poli, Hialy Cristina Camargos
core +1 more source
ROS-Scavenging Multifunctional Microneedle Patch Facilitating Wound Healing. [PDF]
Adv Healthc MaterA reactive oxygen species (ROS) scavenging and immunomodulatory microneedle patch based on hyaluronic acid methacrylate (HaMA) and Flightless I (Flii)‐siRNA‐laden arginine functionalized poly (β‐amino ester)/alginate particles is developed for chronic wound healing applications.
Kharaziha M +4 more
europepmc +2 more sources
Bioabsorbable Endovascular Adhesive Tape (BEAT) for Improving Vascular Regeneration
Advanced Science, EarlyView.A bioabsorbable endovascular adhesive tape (BEAT) platform based on a hierarchical polyelectrolyte complex is developed to enhance drug delivery in the DCB system. The coating enables rapid transfer to the vessel, provides short‐term mechanical support, and promotes both immediate transfer and long‐term retention of drugs at the lesion site.
Jiarong Wang +13 more
wiley +1 more source
Proteomic investigation of the MDM2 interactome and linear motif interactions [PDF]
, 2011 The oncoprotein MDM2 has an integral role in cancer development via multiple signalling pathways. Two proteomic mass spectrometry screens, label-free with spectral counting quantitation and 8-plex iTRAQ were used to identify proteins up or downregulated ...
Nicholson, Judith
core
Multifactorial Screening for Fine‐Scale Selection of CCS Industrial Clusters and Hubs in Brazil
Greenhouse Gases: Science and Technology, EarlyView.ABSTRACT As Brazil moves toward implementing its decarbonization commitments, carbon capture and storage (CCS) hubs are emerging as a key pathway for large‐scale CO2 abatement in hard‐to‐abate sectors. This paper presents a multifactorial, data‐driven framework to screen and prioritize potential CCS industrial clusters and hubs across Brazilian regions,
Gustavo P. Oliveira +5 more
wiley +1 more source
pH‐Responsive Nanoparticle‐Coated Calcium Phosphate Granules for Bone Cancer Therapy
Small, EarlyView.We report β‐TCP granules functionalized with selenium‐doped mesoporous silica nanoparticles through pH‐responsive imine–alendronate interfacial linkers, enabling stable nanoparticle immobilization under physiological conditions and selective release in the acidic osteosarcoma microenvironment.
Lei He +3 more
wiley +1 more source