Results 241 to 250 of about 8,474,325 (290)

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

Predicting the Mechanical Properties of Super Large Aggregate Asphalt Mixture from Volumetric Parameters Using Back Propagation Neural Networks. [PDF]

Materials (Basel)
Ji X, Yang J, Yuan T, Ma J, Liu J, Zhang X, Wang B, Pu C, Zhu S.   +8 more
europepmc   +1 more source

From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits

Advanced Science, EarlyView.
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang, Meng Chen, Guanchen Li, Ruifeng Liu, Yingxin Wang, Ziran Zhao   +5 more
wiley   +1 more source

A BSCB‐Penetrating Nanoplatform for Enhanced Luteolin Delivery in PRMT2‐Targeted Epigenetic Therapy of Spinal Cord Injury

Advanced Science, EarlyView.
In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang, Bo Jin, Shipian Li, Qianxi Ouyang, Yu Xiao, Jiaxin Wen, Yehua Lai, Ping Wang, Yongjun Wang, Xuejun Cui, Weian Zhang, Min Yao   +11 more
wiley   +1 more source

An efficient brain tumor classification system with accurate recognition and complementary downsampling blocks. [PDF]

PLoS One
Zhang J, Cai C, Tan X, Chen W, Zhao X, Du G, Jiang H.   +6 more
europepmc   +1 more source

Deep learning radiomics model for lymph node metastases prediction: a diagnostic study. [PDF]

Gland Surg
Li Y, Wu S, Qiu J, Meng L, Zhang M, Cai H, Xu J, Zhang W, Zhu Y, Peng B.   +9 more
europepmc   +1 more source

Research on the Performance Prediction of Fly Ash Slurry by Neural Network Based on Information Bottleneck Theory and Attention Mechanism. [PDF]

Materials (Basel)
Deng B, Li Z, Lai Y, Feng Y, Sun B, Zhang R, Bai Y.   +6 more
europepmc   +1 more source