Results 101 to 110 of about 1,022,317 (308)

Development of ZHPV16E7- granzyme B immunoaffitoxin: dual mechanisms targeting hpv16-positive cervical cancer through epithelial-mesenchymal transition inhibition and cell death

[EN] Introduction Cervical cancer, predominantly caused by high-risk human papillomavirus (HPV), remains a major global health challenge. HPV16 is the most prevalent type, and its oncoprotein E7 promotes epithelial-mesenchymal transition (EMT), a ...
Yang, Jiani, Li, Wenshu, Tan, Xiaochun, Wan, Kairong, Jing, Xishang, Li, Yanheng, Zhang, Lifang, Feng, Sicong, Xie, Zhenyun   +8 more
core   +1 more source

A New Model for Interactive Group Decision Making with Intuitionistic Fuzzy Preference Relations [PDF]

, 2016
[EN] A new method is proposed to solve the interactive group decision making problem in which the preference information takes the form of intuitionistic fuzzy preference relations.
Zeng ,Shouzhen, Zhu, Facang, Palacios Marqués, Daniel   +2 more
core   +1 more source

Dynamic Analysis of Industrial Carbon Footprint and Carbon-Carrying Capacity of Zhejiang Province in China

, 2022
In studying the industrial carbon emissions in Zhejiang Province from 2015 to 2019, this paper calculates the carbon footprint, carbon-carrying capacity, net carbon footprint, and carbon footprint intensity of Zhejiang Province.
Xiangyi Lin, Hongyun Luo
core   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

Advanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn, Wenjing Wang, Yao Qin, Lili Yan, Stephan Scheeff, Xu He, Qiong Wu, Yue Lin, Jinsai Shang, Xin Ye, Jing Liu, Kailei Sun, Chun Wai Yeung, Junzhe Huang, Zhenghui Chen, Xiaodong Liu, Yiqun Geng, Shannon Wing Ngor Au, Bonaventure Y. Ip, Ho Ko, Billy Wai‐Lung Ng   +20 more
wiley   +1 more source

Studies on the population number of waterfowls in Zhejing Province

浙江大学学报. 农业与生命科学版, 2001
The population number, density and diversity of waterfowls in Zhejiang Province were surveyed from April 1997 to July 1999, with the systematic sampling, line transect and point count methods.7 orders, 13 families and 97 species of waterfowl with 53.6 ...
LIU An-xing, CHEN Zheng-hai, DING Ping, SUN Meng-jun, DU Qun   +4 more
doaj   +1 more source

Occurrence and Exposure Assessment of Zearalenone in the Zhejiang Province, China

Toxins
This study aims to examine the hazards of zearalenone (ZEN) to humans and assess the risk of dietary exposure to ZEN, particularly in relation to precocious puberty in children from the Zhejiang Province. The test results from five types of food from the Zhejiang Province show that corn oil has the highest detection rate of 87.82%. The levels of ZEN do
Zijie Lu, Ronghua Zhang, Pinggu Wu, Dong Zhao, Jiang Chen, Xiaodong Pan, Jikai Wang, Hexiang Zhang, Xiaojuan Qi, Qin Weng, Shufeng Ye, Biao Zhou   +11 more
openaire   +3 more sources

A novel bispecific affitoxin simultaneously targeting E7 of HPV16/18 types: superior anti-tumor activity and EMT reversal in HPV-driven cervical cancer therapy

[EN] BackgroundSustained infection with high-risk HPV of the 16 and 18 types is accounted for nearly 75% of cervical cancer (CC), but now there is an absence of agents aimed at eradicating HPV infections.
Li, Wenshu, Wan, Kairong, Jing, Xishang, Yu, Lijun, Li, Yanheng, Zhang, Lifang, Wu, Junze, Xie, Zhenyun, Feng, Sicong   +8 more
core   +1 more source

A Worm‐Inspired Origami Robot with Multimodal Locomotion for Adaptive Mobility in Complex Pipeline Environments

Advanced Science, EarlyView.
An origami worm‐inspired robot achieves multimodal locomotion in confined pipelines through mechatronic integration that embeds actuation, control, and communication within each origami module. Large, reversible configuration and dimensional changes enable 25 gaits synthesized by a unified framework across peristaltic, inchworm, and wheel‐rolling modes
Qiwei Zhang, Kangning Tan, Zihan He, Hongsen Pang, Yanjie Wang, Hongbin Fang, Jian Xu   +6 more
wiley   +1 more source

Application of the Theory-Clinical-Community Three-Stage Training Model in General Practitioner Cultivation: A Retrospective Cross-Sectional Survey of an in-Service Continuing Professional Development Program

Advances in Medical Education and Practice
Weilin Li,1,* Weihong Zhao,2,* XinYi Mei,1 Wei Zhou,3 Beibei Qin,3 Shuangyan Qiu,1 Tao-Hsin Tung,4 Xiang Jin51Department of Education, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang ...
Li W, Zhao W, Mei X, Zhou W, Qin B, Qiu S, Tung TH, Jin X   +7 more
doaj  

Do new quality productivity and international trade have a positive impact on common prosperity? [PDF]

Problems and Perspectives in Management
Type of the article: Research Article AbstractThis study addresses the critical need to understand how emerging economic drivers can facilitate common prosperity by empirically examining the mechanisms by which new quality productivity and international
Serhii Bashlai, Shenglan Xu, Tеtiana Oliiynyk, Roman Oleksiienko, Evhen Oliinyk, Inessa Yarova, Fedir Zhuravka   +6 more
doaj   +1 more source